LAPTM4A blocking peptide

LAPTM4A Antibody (N-term) Blocking peptide

• Gene Names: LAPTM4A; MBNT; Mtrp; LAPTM4; HUMORF13
• Synonyms: LAPTM4A; LAPTM4A Antibody (N-term) Blocking peptide; Lysosomal-associated transmembrane protein 4A; Golgi 4-transmembrane-spanning transporter MTP; KIAA0108; LAPTM4; MBNT; MTRP; LAPTM4A blocking peptide

• Specificity: The synthetic peptide sequence used to generate the antibody was selected from the N-term region of LAPTM4A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 233

• Cellular Location: Endomembrane system; Multi- pass membrane protein. Note: May reside in an intracellular membrane-bound compartment.
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for LAPTM4A blocking peptide

May function in the transport of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of an intracellular membrane-bound compartment.

NCBI and Uniprot Product Information

• NCBI GI #: 3122413
• NCBI GeneID: 9741
• UniProt Accession #: Q15012; Q6UW22
• Molecular Weight: 26,801 Da
• NCBI Official Full Name: Lysosomal-associated transmembrane protein 4A
• NCBI Official Synonym Full Names: lysosomal protein transmembrane 4 alpha
• NCBI Official Symbol: LAPTM4A
• NCBI Official Synonym Symbols: MBNT; Mtrp; LAPTM4; HUMORF13
• NCBI Protein Information: lysosomal-associated transmembrane protein 4A
• UniProt Protein Name: Lysosomal-associated transmembrane protein 4A
• Protein Family: Lysosomal-associated transmembrane protein
• UniProt Gene Name: LAPTM4A
• UniProt Synonym Gene Names: KIAA0108; LAPTM4; MBNT; MTRP
• UniProt Entry Name: LAP4A_HUMAN

NCBI Description

This gene encodes a protein that has four predicted transmembrane domains. The function of this gene has not yet been determined; however, studies in the mouse homolog suggest a role in the transport of small molecules across endosomal and lysosomal membranes. [provided by RefSeq, Jul 2008]

Uniprot Description

LAPTM4A: May function in the transport of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of an intracellular membrane-bound compartment. Belongs to the LAPTM4/LAPTM5 transporter family.

Protein type: Membrane protein, multi-pass; Vesicle; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2p24.1

Cellular Component: Golgi apparatus; membrane