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MN1 blocking peptide

MN1 Antibody (Center) Blocking peptide

Gene Names
MN1; MGCR; MGCR1; MGCR1-PEN; dJ353E16.2
Synonyms
MN1; MN1 Antibody (Center) Blocking peptide; Probable tumor suppressor protein MN1; MN1 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
1320
Tissue Location
Ubiquitously expressed. Highest levels in skeletal muscle
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for MN1 blocking peptide
May play a role in tumor suppression.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
136,001 Da
NCBI Official Full Name
Transcriptional activator MN1
NCBI Official Synonym Full Names
MN1 proto-oncogene, transcriptional regulator
NCBI Official Symbol
MN1
NCBI Official Synonym Symbols
MGCR; MGCR1; MGCR1-PEN; dJ353E16.2
NCBI Protein Information
transcriptional activator MN1
UniProt Protein Name
Transcriptional activator MN1
Protein Family
UniProt Gene Name
MN1
UniProt Entry Name
MN1_HUMAN

NCBI Description

Meningioma 1 (MN1) contains two sets of CAG repeats. It is disrupted by a balanced translocation (4;22) in a meningioma, and its inactivation may contribute to meningioma 32 pathogenesis. [provided by RefSeq, Jul 2008]

Uniprot Description

MN1: May play a role in tumor suppression. A chromosomal aberration involving MN1 may be a cause of acute myeloid leukemia (AML). Translocation t(12;22)(p13;q11) with TEL. Defects in MN1 involved in the development of meningiomas, slowly growing benign tumors derived from the arachnoidal cap cells of the leptomeninges, the soft coverings of the brain and spinal cord. Meningiomas are believed to be the most common primary tumors of the central nervous system in man.

Protein type: Transcription, coactivator/corepressor; Nuclear receptor co-regulator; Tumor suppressor

Chromosomal Location of Human Ortholog: 22q12.1

Disease: Meningioma, Familial, Susceptibility To

Research Articles on MN1

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Product Notes

The MN1 mn1 (Catalog #AAA9219350) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "MN1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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