Western Blot (WB)
(DCT Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the DCT antibody detected the DCT protein (arrow).)
Rabbit anti-Human DCT Polyclonal Antibody | anti-DCT antibody
DCT Antibody (Center)
Gene Names
DCT; TRP-2; TYRP2
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
DCT; Polyclonal Antibody; DCT Antibody (Center); L-dopachrome tautomerase; DT; L-dopachrome Delta-isomerase; Tyrosinase-related protein 2; TRP-2; TRP2; TYRP2; anti-DCT antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This DCT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-314 amino acids from the Central region of human DCT.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
286-314
Sequence Length
552
Applicable Applications for anti-DCT antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(DCT Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the DCT antibody detected the DCT protein (arrow).)
Western Blot (WB)
(DCT Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the DCT antibody detected the DCT protein (arrow).)
Related Product Information for anti-DCT antibody
DCT is involved in regulating eumelanin and phaeomelanin levels.
Product Categories/Family for anti-DCT antibody
References
Sendoel, A., et al. Nature 465(7298):577-583(2010)
Khong, H.T., et al. J. Immunol. 168(2):951-956(2002)
Sugimoto, H., et al. Biochemistry 38(11):3268-3279(1999)
Nishihira, J., et al. Biochem. Biophys. Res. Commun. 243(2):538-544(1998)
Sugimoto, H., et al. J. Struct. Biol. 120(1):105-108(1997)
Khong, H.T., et al. J. Immunol. 168(2):951-956(2002)
Sugimoto, H., et al. Biochemistry 38(11):3268-3279(1999)
Nishihira, J., et al. Biochem. Biophys. Res. Commun. 243(2):538-544(1998)
Sugimoto, H., et al. J. Struct. Biol. 120(1):105-108(1997)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
59145
NCBI Official Full Name
L-dopachrome tautomerase isoform 2
NCBI Official Synonym Full Names
dopachrome tautomerase
NCBI Official Symbol
DCT
NCBI Official Synonym Symbols
TRP-2; TYRP2
NCBI Protein Information
L-dopachrome tautomerase
UniProt Protein Name
L-dopachrome tautomerase
Protein Family
UniProt Gene Name
DCT
UniProt Synonym Gene Names
TYRP2; DCT; DT; TRP-2; TRP2
UniProt Entry Name
TYRP2_HUMAN
Uniprot Description
DCT: Involved in regulating eumelanin and phaeomelanin levels. Belongs to the tyrosinase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell development/differentiation; Amino Acid Metabolism - tyrosine; EC 5.3.3.12; Membrane protein, integral; Isomerase
Chromosomal Location of Human Ortholog: 13q32
Cellular Component: melanosome membrane; melanosome; integral to membrane; cytosol
Molecular Function: copper ion binding; dopachrome isomerase activity; oxidoreductase activity
Biological Process: neuroblast division in the ventricular zone; positive regulation of neuroblast proliferation; epidermis development; pigmentation during development; melanin biosynthetic process from tyrosine; cell development
Research Articles on DCT
Similar Products
Product Notes
The DCT dct (Catalog #AAA9215218) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 286-314. The DCT Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DCT can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the DCT dct for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DCT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
