Western Blot (WB)
(RPN1 Antibody (C-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the RPN1 antibody detected the RPN1 protein (arrow).)
Rabbit RPN1 Polyclonal Antibody | anti-RPN1 antibody
RPN1 Antibody (C-term)
Western Blot (WB)
(RPN1 Antibody (C-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the RPN1 antibody detected the RPN1 protein (arrow).)
Western Blot (WB)
(RPN1 Antibody (C-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the RPN1 antibody detected the RPN1 protein (arrow).)
only in the rough endoplasmic reticulum. The encoded protein is
part of an N-oligosaccharyl transferase complex that links high
mannose oligosaccharides to asparagine residues found in the
Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This
protein forms part of the regulatory subunit of the 26S proteasome
and may mediate binding of ubiquitin-like domains to this
proteasome.
Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3558-3566(2008)
Wilson, C.M., et al. Proc. Natl. Acad. Sci. U.S.A. 105(28):9534-9539(2008)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Chi, A., et al. J. Proteome Res. 5(11):3135-3144(2006)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein forms part of the regulatory subunit of the 26S proteasome and may mediate binding of ubiquitin-like domains to this proteasome. [provided by RefSeq, Jul 2008]
Uniprot Description
RPN1: Essential subunit of N-oligosaccharyl transferase enzyme which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Belongs to the OST1 family.
Protein type: Membrane protein, integral; Glycan Metabolism - N-glycan biosynthesis; EC 2.4.99.18; Transferase
Chromosomal Location of Human Ortholog: 3q21.3
Cellular Component: endoplasmic reticulum membrane; membrane; rough endoplasmic reticulum; oligosaccharyl transferase complex; integral to membrane; melanosome
Molecular Function: protein binding; dolichyl-diphosphooligosaccharide-protein glycotransferase activity
Biological Process: SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; translation; protein modification process; gene expression; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification
Research Articles on RPN1
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Product Notes
The RPN1 rpn1 (Catalog #AAA9215018) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 559-587. The RPN1 Antibody (C-term) reacts with Human (Predicted Reactivity: Monkey, Pig, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's RPN1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the RPN1 rpn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RPN1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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