Rabbit FAU Polyclonal Antibody | anti-FAU antibody

FAU Antibody (Center)

Cat. Num. AAA9214703

• Gene Names: FAU; S30; FAU1; Fub1; Fubi; asr1; RPS30; MNSFbeta
• Reactivity: Human (Predicted Reactivity: Bovine, Hamster, Mouse, Pig, Rat)
• Applications: Western Blot, ELISA, Immunohistochemistry
• Purity: Purified Rabbit Polyclonal Antibody (Pab)
• Synonyms: FAU; Polyclonal Antibody; FAU Antibody (Center); Ubiquitin-like protein FUBI; anti-FAU antibody

• Host: Rabbit
• Reactivity: Human (Predicted Reactivity: Bovine, Hamster, Mouse, Pig, Rat)
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Specificity: This FAU antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-93 amino acids from the center region of human FUBI.
• Purity/Purification: Purified Rabbit Polyclonal Antibody (Pab)
• Form/Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Concentration: Vial Concentration: 0.5 (varies by lot)
• Sequence Positions: 60-93
• Sequence Length: 74

• Applicable Applications for anti-FAU antibody: Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
• Application Notes: WB~~1:1000
• Antigen Type: Synthetic Peptide
• Antigen Source: HUMAN
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Western blot analysis of anti-FUBI Center Pab (MBS9214703) in Hela and T47D cell line lysates. FUBI Center(arrow) was detected using the purified Pab.)

Immunohistochemistry (IHC)

(Formalin-fixed and paraffin-embedded human colon carcinoma reacted with FUBI Antibody (Center) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)

Related Product Information for anti-FAU antibody

This gene is the cellular homolog of the fox sequence in the Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV). It encodes a fusion protein consisting of the ubiquitin-like protein fubi at the N terminus and ribosomal protein S30 at the C terminus. It has been proposed that the fusion protein is post-translationally processed to generate free fubi and free ribosomal protein S30. Fubi is a member of the ubiquitin family, and ribosomal protein S30 belongs to the S30E family of ribosomal proteins. Whereas the function of fubi is currently unknown, ribosomal protein S30 is a component of the 40S subunit of the cytoplasmic ribosome. Pseudogenes derived from this gene are present in the genome. Similar to ribosomal protein S30, ribosomal proteins S27a and L40 are synthesized as fusion proteins with ubiquitin.

Product Categories/Family for anti-FAU antibody

Cell Biology

References

Rossman, T.G., et al., Oncogene 22(12):1817-1821 (2003).
Kenmochi, N., et al., Genome Res. 8(5):509-523 (1998).
Vladimirov, S.N., et al., Eur. J. Biochem. 239(1):144-149 (1996).
Kas, K., et al., Genomics 17(2):387-392 (1993).
Michiels, L., et al., Oncogene 8(9):2537-2546 (1993).

NCBI and Uniprot Product Information

• NCBI GI #: 4503659
• NCBI GeneID: 2197
• NCBI Accession #: NP_001988.1
• NCBI GenBank Nucleotide #: NM_001997.4
• UniProt Accession #: P35544; Q9H5V4; P62861
• Molecular Weight: 7760
• NCBI Official Full Name: ubiquitin-like protein fubi and ribosomal protein S30
• NCBI Official Synonym Full Names: Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed
• NCBI Official Symbol: FAU
• NCBI Official Synonym Symbols: S30; FAU1; Fub1; Fubi; asr1; RPS30; MNSFbeta
• NCBI Protein Information: ubiquitin-like protein fubi and ribosomal protein S30
• UniProt Protein Name: Ubiquitin-like protein FUBI
• Protein Family: 40S ribosomal protein
• UniProt Gene Name: FAU
• UniProt Entry Name: UBIM_HUMAN

NCBI Description

This gene is the cellular homolog of the fox sequence in the Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV). It encodes a fusion protein consisting of the ubiquitin-like protein fubi at the N terminus and ribosomal protein S30 at the C terminus. It has been proposed that the fusion protein is post-translationally processed to generate free fubi and free ribosomal protein S30. Fubi is a member of the ubiquitin family, and ribosomal protein S30 belongs to the S30E family of ribosomal proteins. Whereas the function of fubi is currently unknown, ribosomal protein S30 is a component of the 40S subunit of the cytoplasmic ribosome and displays antimicrobial activity. Pseudogenes derived from this gene are present in the genome. Similar to ribosomal protein S30, ribosomal proteins S27a and L40 are synthesized as fusion proteins with ubiquitin. [provided by RefSeq, Nov 2014]

Uniprot Description

UBIM: This gene is the cellular homolog of the fox sequence in the Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV). It encodes a fusion protein consisting of the ubiquitin-like protein fubi at the N terminus and ribosomal protein S30 at the C terminus. It has been proposed that the fusion protein is post-translationally processed to generate free fubi and free ribosomal protein S30. Fubi is a member of the ubiquitin family, and ribosomal protein S30 belongs to the S30E family of ribosomal proteins. Whereas the function of fubi is currently unknown, ribosomal protein S30 is a component of the 40S subunit of the cytoplasmic ribosome. Pseudogenes derived from this gene are present in the genome. Similar to ribosomal protein S30, ribosomal proteins S27a and L40 are synthesized as fusion proteins with ubiquitin. [provided by RefSeq, Jul 2008]

Protein type: Ubiquitin-like modifier

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: extracellular space; small ribosomal subunit; cytosol

Molecular Function: structural constituent of ribosome; RNA binding

Biological Process: SRP-dependent cotranslational protein targeting to membrane; translation; viral reproduction; translational termination; viral infectious cycle; defense response to Gram-positive bacterium; translational elongation; cellular protein metabolic process; innate immune response in mucosa; translational initiation; mRNA catabolic process, nonsense-mediated decay; antibacterial humoral response; viral transcription; gene expression