Western Blot (WB)
(KCNJ18 Antibody (N-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the KCNJ18 antibody detected the KCNJ18 protein (arrow).)
Rabbit anti-Human KCNJ18 Polyclonal Antibody | anti-KCNJ18 antibody
KCNJ18 Antibody (N-term)
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
KCNJ18; Polyclonal Antibody; KCNJ18 Antibody (N-term); Inward rectifier potassium channel 18; Inward rectifier K(+) channel Kir26; Potassium channel; inwardly rectifying subfamily J member 18; anti-KCNJ18 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This KCNJ18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-122 amino acids from the N-terminal region of human KCNJ18.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
94-122
Sequence Length
433
Applicable Applications for anti-KCNJ18 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(KCNJ18 Antibody (N-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the KCNJ18 antibody detected the KCNJ18 protein (arrow).)
Western Blot (WB)
(KCNJ18 Antibody (N-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the KCNJ18 antibody detected the KCNJ18 protein (arrow).)
Related Product Information for anti-KCNJ18 antibody
Inwardly rectifying potassium channels, such as KCNJ18,
maintain resting membrane potential in excitable cells and aid in
repolarization of cells following depolarization. KCNJ18 is
primarily expressed in skeletal muscle and is transcriptionally
regulated by thyroid hormone (Ryan et al., 2010 [PubMed
20074522]).
maintain resting membrane potential in excitable cells and aid in
repolarization of cells following depolarization. KCNJ18 is
primarily expressed in skeletal muscle and is transcriptionally
regulated by thyroid hormone (Ryan et al., 2010 [PubMed
20074522]).
References
Ryan, D.P., et al. Cell 140(1):88-98(2010)
NCBI and Uniprot Product Information
NCBI GI #
UniProt Accession #
Molecular Weight
48738
NCBI Official Full Name
Inward rectifier potassium channel 18
UniProt Protein Name
Inward rectifier potassium channel 18
Protein Family
UniProt Gene Name
KCNJ18
UniProt Entry Name
KCJ18_HUMAN
Uniprot Description
KCNJ18: Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ12 subfamily. Up-regulated by triiodothyronine
Protein type: Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: -
Cellular Component: plasma membrane; integral to membrane
Molecular Function: inward rectifier potassium channel activity
Disease: Thyrotoxic Periodic Paralysis, Susceptibility To, 2
Similar Products
Product Notes
The KCNJ18 kcnj18 (Catalog #AAA9213735) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 94-122. The KCNJ18 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's KCNJ18 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the KCNJ18 kcnj18 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KCNJ18, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
