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Western Blot (WB) (TM9SF2 Antibody (N-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the TM9SF2 antibody detected the TM9SF2 protein (arrow).)

Rabbit anti-Human TM9SF2 Polyclonal Antibody | anti-TM9SF2 antibody

TM9SF2 Antibody (N-term)

Gene Names
TM9SF2; P76
Reactivity
Human
Applications
Western Blot, ELISA, Immunohistochemistry
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
TM9SF2; Polyclonal Antibody; TM9SF2 Antibody (N-term); Transmembrane 9 superfamily member 2; p76; anti-TM9SF2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This TM9SF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-140 amino acids from the N-terminal region of human TM9SF2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
111-140
Sequence Length
663
Applicable Applications for anti-TM9SF2 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
WB~~1:1000
IHC-P~~1:10~50
Antigen Type
Synthetic Peptide
Clone Names
RB32604
Antigen Source
HUMAN
Cellular Location
Endosome membrane; Multi-pass membrane protein
Tissue Location
Ubiquitously expressed. Especially abundant in pancreas, highly expressed in kidney, lower levels in heart, brain, skeletal muscle and placenta. Lowest expression in lung and liver.
Preparation and Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(TM9SF2 Antibody (N-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the TM9SF2 antibody detected the TM9SF2 protein (arrow).)

Western Blot (WB) (TM9SF2 Antibody (N-term) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the TM9SF2 antibody detected the TM9SF2 protein (arrow).)

Immunohistochemistry (IHC)

(TM9SF2 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TM9SF2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Immunohistochemistry (IHC) (TM9SF2 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TM9SF2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-TM9SF2 antibody
In the intracellular compartments, may function as a channel or small molecule transporter.
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Colland, F., et al. Genome Res. 14(7):1324-1332(2004)
Dunham, A., et al. Nature 428(6982):522-528(2004)
Schimmoller, F., et al. Gene 216(2):311-318(1998)
Diaz, E., et al. J. Cell Biol. 138(2):283-290(1997)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
75776
NCBI Official Full Name
transmembrane 9 superfamily member 2
NCBI Official Synonym Full Names
transmembrane 9 superfamily member 2
NCBI Official Symbol
TM9SF2
NCBI Official Synonym Symbols
P76
NCBI Protein Information
transmembrane 9 superfamily member 2
UniProt Protein Name
Transmembrane 9 superfamily member 2
UniProt Gene Name
TM9SF2
UniProt Entry Name
TM9S2_HUMAN

NCBI Description

This gene encodes a member of the transmembrane 9 superfamily. The encoded 76 kDa protein localizes to early endosomes in human cells. The encoded protein possesses a conserved and highly hydrophobic C-terminal domain which contains nine transmembrane domains. The protein may play a role in small molecule transport or act as an ion channel. A pseudogene associated with this gene is located on the X chromosome. [provided by RefSeq, Oct 2012]

Uniprot Description

TM9SF2: In the intracellular compartments, may function as a channel or small molecule transporter. Belongs to the nonaspanin (TM9SF) family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 13q32.3

Cellular Component: integral to plasma membrane; endosome membrane; endosome

Biological Process: transport

Research Articles on TM9SF2

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Product Notes

The TM9SF2 tm9sf2 (Catalog #AAA9213224) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 111-140. The TM9SF2 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TM9SF2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000 IHC-P~~1:10~50. Researchers should empirically determine the suitability of the TM9SF2 tm9sf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TM9SF2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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