Western Blot (WB)
(MMEL1 Antibody (N-term) western blot analysis in human Uterus tissue lysates (35ug/lane).This demonstrates the MMEL1 antibody detected the MMEL1 protein (arrow).)
Rabbit anti-Human MMEL1 Polyclonal Antibody | anti-MMEL1 antibody
MMEL1 Antibody (N-term)
Western Blot (WB)
(MMEL1 Antibody (N-term) western blot analysis in human Uterus tissue lysates (35ug/lane).This demonstrates the MMEL1 antibody detected the MMEL1 protein (arrow).)
Western Blot (WB)
(MMEL1 Antibody (N-term) western blot analysis in human Uterus tissue lysates (35ug/lane).This demonstrates the MMEL1 antibody detected the MMEL1 protein (arrow).)
neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME)
family. Family members play important roles in pain perception,
arterial pressure regulation, phosphate metabolism and homeostasis.
This protein is a type II transmembrane protein and is thought to
be expressed as a secreted protein. This gene is expressed mainly
in testis with weak expression in the brain, kidney, and heart.
Hirschfield, G.M., et al. Nat. Genet. 42(8):655-657(2010)
Stahl, E.A., et al. Nat. Genet. 42(6):508-514(2010)
Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart. [provided by RefSeq, Jul 2008]
Uniprot Description
MELL1: Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificity with MME and cleaves peptides at the same amide bond. Belongs to the peptidase M13 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Protease; EC 3.4.24.11
Chromosomal Location of Human Ortholog: 1p36
Cellular Component: Golgi apparatus; extracellular space; endoplasmic reticulum; integral to membrane
Molecular Function: zinc ion binding; metalloendopeptidase activity
Biological Process: proteolysis
Research Articles on MMEL1
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Product Notes
The MMEL1 mmel1 (Catalog #AAA9209159) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 50-78. The MMEL1 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MMEL1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the MMEL1 mmel1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MMEL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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