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Western Blot (WB) (COG3 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the COG3 antibody detected the COG3 protein (arrow).)

Rabbit COG3 Polyclonal Antibody | anti-COG3 antibody

COG3 Antibody (C-term)

Gene Names
COG3; SEC34
Reactivity
Human (Predicted Reactivity: Mouse)
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
COG3; Polyclonal Antibody; COG3 Antibody (C-term); Conserved oligomeric Golgi complex subunit 3; COG complex subunit 3; Component of oligomeric Golgi complex 3; Vesicle-docking protein SEC34 homolog; p94; SEC34; anti-COG3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Mouse)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This COG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 666-695 amino acids from the C-terminal region of human COG3.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.27 (varies by lot)
Sequence Positions
666-695
Sequence Length
444
Applicable Applications for anti-COG3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(COG3 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the COG3 antibody detected the COG3 protein (arrow).)

Western Blot (WB) (COG3 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the COG3 antibody detected the COG3 protein (arrow).)
Related Product Information for anti-COG3 antibody
The protein encoded by this gene has similarity to a yeast
protein. It seems to be part of a peripheral membrane protein
complex localized on cis/medial Golgi cisternae where it may
participate in tethering intra-Golgi transport vesicles. [provided
by RefSeq].
Product Categories/Family for anti-COG3 antibody
References
Laufman, O., et al. EMBO J. 28(14):2006-2017(2009)
Shestakova, A., et al. Traffic 7(2):191-204(2006)
Loh, E., et al. J. Biol. Chem. 279(23):24640-24648(2004)
Dunham, A., et al. Nature 428(6982):522-528(2004)
Gevaert, K., et al. Nat. Biotechnol. 21(5):566-569(2003)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
94096
NCBI Official Full Name
conserved oligomeric Golgi complex subunit 3
NCBI Official Synonym Full Names
component of oligomeric golgi complex 3
NCBI Official Symbol
COG3
NCBI Official Synonym Symbols
SEC34
NCBI Protein Information
conserved oligomeric Golgi complex subunit 3
UniProt Protein Name
Conserved oligomeric Golgi complex subunit 3
UniProt Gene Name
COG3
UniProt Synonym Gene Names
SEC34; COG complex subunit 3
UniProt Entry Name
COG3_HUMAN

NCBI Description

This gene encodes a component of the conserved oligomeric Golgi (COG) complex which is composed of eight different subunits and is required for normal Golgi morphology and localization. Defects in the COG complex result in multiple deficiencies in protein glycosylation. The protein encoded by this gene is involved in ER-Golgi transport.[provided by RefSeq, Jun 2011]

Uniprot Description

COG3: Involved in ER-Golgi transport. Belongs to the COG3 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 13q14.13

Cellular Component: nucleoplasm; Golgi apparatus; cis-Golgi network; cytoplasm; plasma membrane; Golgi transport complex

Molecular Function: protein binding; protein transporter activity

Biological Process: intra-Golgi vesicle-mediated transport; intracellular protein transport; ER to Golgi vesicle-mediated transport; retrograde transport, vesicle recycling within Golgi; protein stabilization; protein localization in organelle; retrograde vesicle-mediated transport, Golgi to ER; protein amino acid glycosylation; Golgi organization and biogenesis

Research Articles on COG3

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Product Notes

The COG3 cog3 (Catalog #AAA9208346) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 666-695. The COG3 Antibody (C-term) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's COG3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the COG3 cog3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "COG3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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