Western Blot (WB)
(MOSPD2 Antibody (N-term) (MBS9208011) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MOSPD2 antibody detected the MOSPD2 protein (arrow).)
Rabbit anti-Human MOSPD2 Polyclonal Antibody | anti-MOSPD2 antibody
MOSPD2 Antibody (N-term)
Reactivity
Human
Applications
Western Blot, ELISA, Immunohistochemistry
Purity
This antibody is purified through a protein A column, followed by peptide affinity purification.
Synonyms
MOSPD2; Polyclonal Antibody; MOSPD2 Antibody (N-term); Motile sperm domain-containing protein 2; anti-MOSPD2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This MOSPD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-40 amino acids from the N-terminal region of human MOSPD2.
Purity/Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Sequence Positions
11-40
Sequence Length
455
Applicable Applications for anti-MOSPD2 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC-P)
Application Notes
WB~~1:1000
IHC-P~~1:10~50
IHC-P~~1:10~50
Function
Endoplasmic reticulum-anchored receptor which modulates interorganelle contacts by interacting with other organelle-bound proteins via their FFAT motif (PubMed: 29858488). Might have a more important role inendoplasmic reticulum and endosomes contacts (PubMed: 29858488). Promotes migration of primary monocytes and neutrophils, in response to various chemokines (PubMed: 28137892).
Cellular Location
Endoplasmic reticulum membrane; Single-pass type IV membrane protein Note=Localization to contact sites involving the endoplasmic reticulum and several organelles is regulated by interaction with proteins containing FFAT motif.
Tissue Location
Highly expressed in CD14(+) monocytes, and at lower levels in neutrophils. Does not show significant expression in B-cells or T-cells.
Preparation and Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(MOSPD2 Antibody (N-term) (MBS9208011) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MOSPD2 antibody detected the MOSPD2 protein (arrow).)
Western Blot (WB)
(MOSPD2 Antibody (N-term) (MBS9208011) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MOSPD2 antibody detected the MOSPD2 protein (arrow).)
Immunohistochemistry (IHC)
(MOSPD2 Antibody (N-term) (MBS9208011) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MOSPD2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(MOSPD2 Antibody (N-term) (MBS9208011) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MOSPD2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-MOSPD2 antibody
The specific function of this protein remains unknown.
References
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Calculated MW: 59746
NCBI Official Full Name
motile sperm domain-containing protein 2 isoform 2
NCBI Official Synonym Full Names
motile sperm domain containing 2
NCBI Official Symbol
MOSPD2
NCBI Protein Information
motile sperm domain-containing protein 2
UniProt Protein Name
Motile sperm domain-containing protein 2
Protein Family
UniProt Gene Name
MOSPD2
UniProt Entry Name
MSPD2_HUMAN
Uniprot Description
MOSPD2: 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: Xp22.2
Cellular Component: membrane; integral to membrane
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Product Notes
The MOSPD2 mospd2 (Catalog #AAA9208011) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 11-40. The MOSPD2 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MOSPD2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC-P). WB~~1:1000 IHC-P~~1:10~50. Researchers should empirically determine the suitability of the MOSPD2 mospd2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MOSPD2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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