Western Blot (WB)
(CCDC8 Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CCDC8 antibody detected the CCDC8 protein (arrow).)
Rabbit anti-Human CCDC8 Polyclonal Antibody | anti-CCDC8 antibody
CCDC8 Antibody (C-term)
Western Blot (WB)
(CCDC8 Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CCDC8 antibody detected the CCDC8 protein (arrow).)
Western Blot (WB)
(CCDC8 Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CCDC8 antibody detected the CCDC8 protein (arrow).)
Immunohistochemistry (IHC)
(CCDC8 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CCDC8 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(CCDC8 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CCDC8 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a cofactor required for p53-mediated apoptosis following DNA damage, and may also play a role in growth through interactions with the cytoskeletal adaptor protein obscurin-like 1. Mutations in this gene are a cause of 3M syndrome-3 (3M3). [provided by RefSeq, Dec 2011]
Uniprot Description
CCDC8: Defects in CCDC8 are the cause of 3M syndrome type 3 (3M3). A disorder characterized by poor postnatal growth and distinctive facial features, including triangular facies, frontal bossing, fleshy tipped nose, and fleshy lips. Other features may include skeletal anomalies and prominent heels.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 19q13.32
Cellular Component: centrosome; cytoplasm; plasma membrane
Biological Process: regulation of mitosis; microtubule cytoskeleton organization and biogenesis
Disease: Three M Syndrome 3
Research Articles on CCDC8
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Product Notes
The CCDC8 ccdc8 (Catalog #AAA9207745) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 390-418. The CCDC8 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CCDC8 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the CCDC8 ccdc8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCDC8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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