Western Blot (WB)
(PKP3 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the PKP3 antibody detected the PKP3 protein (arrow).)
Rabbit PKP3 Polyclonal Antibody | anti-PKP3 antibody
PKP3 Antibody (C-term)
Reactivity
Human (Predicted Reactivity: Bovine, Mouse)
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
PKP3; Polyclonal Antibody; PKP3 Antibody (C-term); Plakophilin-3; anti-PKP3 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Bovine, Mouse)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This PKP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 766-794 amino acids from the C-terminal region of human PKP3.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
766-794
Sequence Length
797
Applicable Applications for anti-PKP3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(PKP3 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the PKP3 antibody detected the PKP3 protein (arrow).)
Western Blot (WB)
(PKP3 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the PKP3 antibody detected the PKP3 protein (arrow).)
Related Product Information for anti-PKP3 antibody
This gene encodes a member of the arm-repeat (armadillo)
and plakophilin gene families. Plakophilin proteins contain
numerous armadillo repeats, localize to cell desmosomes and nuclei,
and participate in linking cadherins to intermediate filaments in
the cytoskeleton. This protein may act in cellular
desmosome-dependent adhesion and signaling pathways. [provided by
RefSeq].
and plakophilin gene families. Plakophilin proteins contain
numerous armadillo repeats, localize to cell desmosomes and nuclei,
and participate in linking cadherins to intermediate filaments in
the cytoskeleton. This protein may act in cellular
desmosome-dependent adhesion and signaling pathways. [provided by
RefSeq].
Product Categories/Family for anti-PKP3 antibody
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Valladares-Ayerbes, M., et al. Cancer Epidemiol. Biomarkers Prev. 19(6):1432-1440(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Kundu, S.T., et al. Int. J. Cancer 123(10):2303-2314(2008)
Valladares-Ayerbes, M., et al. Cancer Detect. Prev. 32(3):236-250(2008)
Valladares-Ayerbes, M., et al. Cancer Epidemiol. Biomarkers Prev. 19(6):1432-1440(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Kundu, S.T., et al. Int. J. Cancer 123(10):2303-2314(2008)
Valladares-Ayerbes, M., et al. Cancer Detect. Prev. 32(3):236-250(2008)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
87082
NCBI Official Full Name
plakophilin-3 isoform PKP3a
NCBI Official Synonym Full Names
plakophilin 3
NCBI Official Symbol
PKP3
NCBI Protein Information
plakophilin-3
UniProt Protein Name
Plakophilin-3
Protein Family
UniProt Gene Name
PKP3
UniProt Entry Name
PKP3_HUMAN
NCBI Description
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]
Uniprot Description
plakophilin 3: a novel armadillo-like protein present in nuclei and desmosomes of epithelial cells and dendritic reticular cells of lymphatic follicles.
Protein type: Cell adhesion
Chromosomal Location of Human Ortholog: 11p15
Cellular Component: desmosome; plasma membrane; intercellular junction; nucleus
Molecular Function: cell adhesion molecule binding
Biological Process: cell-cell adhesion
Research Articles on PKP3
Similar Products
Product Notes
The PKP3 pkp3 (Catalog #AAA9206884) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 766-794. The PKP3 Antibody (C-term) reacts with Human (Predicted Reactivity: Bovine, Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's PKP3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the PKP3 pkp3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PKP3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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