Western Blot (WB)
(S1PR5 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the S1PR5 antibody detected the S1PR5 protein (arrow).)
Rabbit anti-Human S1PR5 Polyclonal Antibody | anti-S1PR5 antibody
S1PR5 Antibody (Center)
Western Blot (WB)
(S1PR5 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the S1PR5 antibody detected the S1PR5 protein (arrow).)
Western Blot (WB)
(S1PR5 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the S1PR5 antibody detected the S1PR5 protein (arrow).)
regulates cell proliferation, apoptosis, motility, and neurite
retraction. Its actions may be both intracellular as a second
messenger and extracellular as a receptor ligand. S1P and the
structurally related lysolipid mediator lysophosphatidic acid (LPA)
signal cells through a set of G protein-coupled receptors known as
EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P
receptors; others (e.g., EDG2; MIM 602282) are LPA
receptors.
Gillies, L., et al. Cell. Signal. 21(5):675-684(2009)
Miron, V.E., et al. Ann. Neurol. 63(1):61-71(2008)
Ulfig, N., et al. Acta Histochem. 106(5):373-378(2004)
Vogler, R., et al. J. Invest. Dermatol. 120(4):693-700(2003)
NCBI and Uniprot Product Information
NCBI Description
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.[supplied by OMIM, Mar 2008]
Uniprot Description
EDG8: Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. Is coupled to both the G(i/0)alpha and G(12) subclass of heteromeric G-proteins. May play a regulatory role in the transformation of radial glial cells into astrocytes and may affect proliferative activity of these cells. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 1
Chromosomal Location of Human Ortholog: 19p13.2
Cellular Component: plasma membrane; integral to membrane
Biological Process: regulation of neuron differentiation
Research Articles on S1PR5
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Product Notes
The S1PR5 s1pr5 (Catalog #AAA9206754) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 219-247. The S1PR5 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's S1PR5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the S1PR5 s1pr5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "S1PR5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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