Western Blot (WB)
(REXO2 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the REXO2 antibody detected the REXO2 protein (arrow).)
Rabbit anti-Human REXO2 Polyclonal Antibody | anti-REXO2 antibody
REXO2 Antibody (Center)
Western Blot (WB)
(REXO2 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the REXO2 antibody detected the REXO2 protein (arrow).)
Western Blot (WB)
(REXO2 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the REXO2 antibody detected the REXO2 protein (arrow).)
carry out functions in DNA repair, replication, and recombination
and in RNA processing and degradation. SFN is a homolog of Orn, a
3-prime-to-5-prime exoribonuclease of E. coli that attacks the free
3-prime hydroxyl group on single-stranded RNA, releasing 5-prime
mononucleotides in a sequential manner.
Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
Ito, S., et al. Photochem. Photobiol. 80(2):281-285(2004)
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
Nguyen, L.H., et al. J. Biol. Chem. 275(34):25900-25906(2000)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a 3'-to-5' exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process. [provided by RefSeq, Nov 2011]
Uniprot Description
REXO2: a 3'-to-5' exoribonuclease specific for small oligoribonucleotides. Active on small (primarily </=5 nucleotides in length) single-stranded RNA and DNA oligomers. May have a role for cellular nucleotide recycling. Two splice variant isoforms have been described: mitochondrial (isoform 1) and nuclear (isoform 2).
Protein type: Hydrolase; EC 3.1.-.-
Chromosomal Location of Human Ortholog: 11q23.2
Cellular Component: focal adhesion; mitochondrion; mitochondrial matrix; nucleolus; mitochondrial intermembrane space; nucleus
Molecular Function: 3'-5'-exoribonuclease activity; nucleic acid binding; 3'-5' exonuclease activity
Biological Process: nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; nucleotide metabolic process
Research Articles on REXO2
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Product Notes
The REXO2 rexo2 (Catalog #AAA9203636) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 129-157. The REXO2 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's REXO2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the REXO2 rexo2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "REXO2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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