Western Blot (WB)
(All lanes : Anti-Scx Antibody (C-term) at 1:2000 dilutionLane 1: mouse cerebellum lysatesLane 2: mouse heart lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 22 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Rabbit anti-Mouse Scx Polyclonal Antibody | anti-Scx antibody
(Mouse) Scx Antibody (C-term)
Western Blot (WB)
(All lanes : Anti-Scx Antibody (C-term) at 1:2000 dilutionLane 1: mouse cerebellum lysatesLane 2: mouse heart lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 22 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Western Blot (WB)
(All lanes : Anti-Scx Antibody (C-term) at 1:2000 dilutionLane 1: mouse cerebellum lysatesLane 2: mouse heart lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 22 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Western Blot (WB)
(Anti-Scx Antibody (C-term)at 1:1000 dilution + mouse lung lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 22 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Western Blot (WB)
(Anti-Scx Antibody (C-term)at 1:1000 dilution + mouse lung lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 22 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Brown D.,et al.Development 126:4317-4329(1999).
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a basic helix-loop-helix type transcription factor involved in mesoderm and heart valve formation. The encoded protein is expressed during embryonic development of tendons and ligaments. The gene product regulates collagen type I gene expression in cardiac fibroblasts and myofibroblasts, and it may play a role in myocardial remodeling. The protein is expressed in the scar area of the adult heart following myocardial infarction. [provided by RefSeq, Feb 2010]
Uniprot Description
SCXA: Plays an early essential role in mesoderm formation, as well as a later role in formation of somite-derived chondrogenic lineages.
Protein type: DNA-binding; Transcription regulation
Cellular Component: transcription factor complex; nucleus
Molecular Function: protein dimerization activity; protein binding; DNA binding; protein heterodimerization activity; sequence-specific DNA binding; bHLH transcription factor binding
Biological Process: transcription from RNA polymerase II promoter; collagen fibril organization; transcription, DNA-dependent; multicellular organismal development; positive regulation of transcription, DNA-dependent; positive regulation of collagen biosynthetic process; BMP signaling pathway; regulation of transcription, DNA-dependent; mesoderm formation; cartilage development; positive regulation of cell proliferation; tissue homeostasis; chondrocyte differentiation; positive regulation of transcription from RNA polymerase II promoter; cell differentiation; negative regulation of transcription, DNA-dependent; endochondral ossification; negative regulation of apoptosis
Research Articles on Scx
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Product Notes
The Scx scx (Catalog #AAA9203066) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The (Mouse) Scx Antibody (C-term) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Scx can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Scx scx for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Scx, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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