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Western Blot (WB) (Mouse Ksr2 Antibody (C-term) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the Ksr2 antibody detected the Ksr2 protein (arrow).)

Rabbit anti-Human Ksr2 Polyclonal Antibody | anti-Ksr2 antibody

Mouse Ksr2 Antibody (C-term)

Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
Ksr2; Polyclonal Antibody; Mouse Ksr2 Antibody (C-term); Kinase suppressor of Ras 2; Ksr2 {ECO:0000312|MGI:MGI:3610315}; anti-Ksr2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This Mouse Ksr2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 808-836 amino acids from the C-terminal region of mouse Ksr2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
808-836
Sequence Length
959
Applicable Applications for anti-Ksr2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
MOUSE
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Mouse Ksr2 Antibody (C-term) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the Ksr2 antibody detected the Ksr2 protein (arrow).)

Western Blot (WB) (Mouse Ksr2 Antibody (C-term) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the Ksr2 antibody detected the Ksr2 protein (arrow).)
Related Product Information for anti-Ksr2 antibody
Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production (By similarity).
Product Categories/Family for anti-Ksr2 antibody
References
Costanzo-Garvey, D.L., et al. Cell Metab. 10(5):366-378(2009) Dougherty, M.K., et al. Mol. Cell 34(6):652-662(2009)

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
108572
NCBI Official Full Name
Kinase suppressor of Ras 2
UniProt Protein Name
Kinase suppressor of Ras 2
Protein Family
UniProt Gene Name
Ksr2
UniProt Entry Name
KSR2_MOUSE

Uniprot Description

KSR2: Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein kinase, TKL; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; EC 2.7.11.1; TKL group; RAF family

Cellular Component: membrane; cytoplasm; plasma membrane; intracellular; cytosol

Molecular Function: transferase activity; protein serine/threonine kinase activity; protein binding; MAP-kinase scaffold activity; mitogen-activated protein kinase kinase binding; metal ion binding; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; ATP binding; protein kinase activity

Biological Process: positive regulation of MAPKKK cascade; calcium-mediated signaling; protein amino acid phosphorylation; phosphorylation

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Product Notes

The Ksr2 ksr2 (Catalog #AAA9202270) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 808-836. The Mouse Ksr2 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Ksr2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Ksr2 ksr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ksr2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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