Immunohistochemistry (IHC)
(DCT Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DCT Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human DCT Polyclonal Antibody | anti-DCT antibody
DCT Antibody (N-term)
WB~~1:1000
Immunohistochemistry (IHC)
(DCT Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DCT Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(DCT Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DCT Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Western Blot (WB)
(Western blot analysis of DCT Antibody (N-term) in A375 cell line lysates (35ug/lane). DCT (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of DCT Antibody (N-term) in A375 cell line lysates (35ug/lane). DCT (arrow) was detected using the purified Pab.)
Khong, H.T., et al. J. Immunol. 168(2):951-956(2002)
Sugimoto, H., et al. Biochemistry 38(11):3268-3279(1999)
NCBI and Uniprot Product Information
Uniprot Description
DCT: Involved in regulating eumelanin and phaeomelanin levels. Belongs to the tyrosinase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 5.3.3.12; Membrane protein, integral; Cell development/differentiation; Amino Acid Metabolism - tyrosine; Isomerase
Chromosomal Location of Human Ortholog: 13q32
Cellular Component: melanosome membrane; melanosome; integral to membrane; cytosol
Molecular Function: copper ion binding; dopachrome isomerase activity; oxidoreductase activity
Biological Process: neuroblast division in the ventricular zone; positive regulation of neuroblast proliferation; epidermis development; pigmentation during development; melanin biosynthetic process from tyrosine; cell development
Research Articles on DCT
Similar Products
Product Notes
The DCT dct (Catalog #AAA9201624) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 62-89. The DCT Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's DCT can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB). IHC~~1:50~100 WB~~1:1000. Researchers should empirically determine the suitability of the DCT dct for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DCT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
