Western Blot (WB)
(Western blot analysis of extracts of A-549 cells, using LTC4S antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit.Exposure time: 90.)
Rabbit anti-Human LTC4S Polyclonal Antibody | anti-LTC4S antibody
LTC4S Polyclonal Antibody
Reactivity
Human
Applications
Western Blot
Purity
Affinity Purification
Synonyms
LTC4S; Polyclonal Antibody; LTC4S Polyclonal Antibody; anti-LTC4S antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Sequence
YRAQVNCSEYFPLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVALAALGLLAHFLPAALRAALLGRLRTLLPWA
Sequence Length
150
Applicable Applications for anti-LTC4S antibody
Western Blot (WB)
Application Notes
WB: 1:500 - 1:2000
Immunogen
A synthetic peptide of human LTC4S
Immunogen Species
Human
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Cellular Location
Endoplasmic reticulum membrane, Multi-pass membrane protein, Nucleus outer membrane
Positive Samples
A-549
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Western Blot (WB)
(Western blot analysis of extracts of A-549 cells, using LTC4S antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit.Exposure time: 90.)
Western Blot (WB)
(Western blot analysis of extracts of A-549 cells, using LTC4S antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit.Exposure time: 90.)
Related Product Information for anti-LTC4S antibody
The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. This gene encodes an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma. This protein localizes to the nuclear envelope and adjacent endoplasmic reticulum.
Product Categories/Family for anti-LTC4S antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Calculated: 16kDa
Observed: 17kDa
Observed: 17kDa
NCBI Official Full Name
leukotriene C4 synthase
NCBI Official Synonym Full Names
leukotriene C4 synthase
NCBI Official Symbol
LTC4S
NCBI Protein Information
leukotriene C4 synthase
UniProt Protein Name
Leukotriene C4 synthase
Protein Family
UniProt Gene Name
LTC4S
UniProt Synonym Gene Names
LTC4 synthase
NCBI Description
The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. This gene encodes an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma. This protein localizes to the nuclear envelope and adjacent endoplasmic reticulum. [provided by RefSeq, Jul 2008]
Uniprot Description
Catalyzes the conjugation of leukotriene A4 with reduced glutathione to form leukotriene C4.
Research Articles on LTC4S
Similar Products
Product Notes
The LTC4S ltc4s (Catalog #AAA9135057) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LTC4S Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's LTC4S can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500 - 1:2000. Researchers should empirically determine the suitability of the LTC4S ltc4s for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: YRAQVNCSEY FPLFLATLWV AGIFFHEGAA ALCGLVYLFA RLRYFQGYAR SAQLRLAPLY ASARALWLLV ALAALGLLAH FLPAALRAAL LGRLRTLLPW A. It is sometimes possible for the material contained within the vial of "LTC4S, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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