Rabbit FKBP42 Polyclonal Antibody | anti-FKBP42 antibody

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) FKBP42 Polyclonal Antibody

• Gene Names: TWD1; ATFKBP42; FK506-BINDING PROTEIN 42; FKBP42; TWD1; TWISTED DWARF 1; UCU2; ULTRACURVATA 2
• Reactivity: Arabidopsis thaliana (Mouse-ear cress)
• Applications: ELISA, Western Blot
• Purity: Protein A/G
• Synonyms: FKBP42; Polyclonal Antibody; Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) FKBP42 Polyclonal Antibody; FKBP42 Antibody; Peptidyl-prolyl cis-trans isomerase FKBP42; PPIase FKBP42; EC 5.2.1.8; 42kDa peptidyl-prolyl isomerase; FK506-binding protein 42; AtFKBP42; Immunophilin FKBP42; Protein TWISTED DWARF 1; Protein ULTRACURVATA 2; Rotamase; FKBP42 TWD1 UCU2 At3g21640 MIL23.21; anti-FKBP42 antibody

• Host: Rabbit
• Reactivity: Arabidopsis thaliana (Mouse-ear cress)
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Protein A/G
• Form/Format: Liquid; Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH7.4

• Applicable Applications for anti-FKBP42 antibody: ELISA (EIA), WB (Western Blot) (ensure identification of antigen)
• Immunogen: Recombinant Arabidopsis thaliana FKBP42 protein
• Conjugation: Non-conjugate
• Modification: Unmodified
• Deliverables: 1. 200ug recombinant immunogen protein/peptide (positive control).; 2. 1mL preimmune serum (negative control); 3. 10mg rabbit polyclonal antibody purified by Protein A/G.
• Quality Guarantee: 1. Antibody purity >90% confirmed by SDS-PAGE.; 2. Antibody titer > 1: 64,000 confirmed by ELISA; 3. Western Blot positive for the immunogen protein (Not applicable for synthetic peptide).
• Complementary Antibody: Customer can choose 1 FREE antibody from the list below. Please specify the catalog # when order:; * 6*His Monoclonal Antibody #MBS1491670; * DYKDDDDK tag Monoclonal Antibody #MBS1493946; * GAPDH Monoclonal Antibody #MBS1495524; * GFP Monoclonal Antibody #MBS1496050; * Myc tag Monoclonal Antibody #MBS1497694; * GST Monoclonal Antibody #MBS1497871; * Sumo tag Monoclonal Antibody #MBS1498878; * Goat Anti-Rabbit IgG (H+L) Antibody; HRP conjugated #MBS7053510; * HA-Tag Monoclonal Antibody #MBS7135631; * E-Tag Monoclonal Antibody #MBS7135632; * TUBA1A Monoclonal Antibody #MBS7135645; * TUBB Monoclonal Antibody #MBS9018332
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

NCBI and Uniprot Product Information

• NCBI GI #: 30686321
• NCBI GeneID: 821718
• NCBI Accession #: NP_188801.2
• NCBI GenBank Nucleotide #: NM_113059.2
• UniProt Accession #: Q9LDC0; Q8RWM0
• Molecular Weight: 41,806 Da
• NCBI Official Full Name: putative peptidyl-prolyl cis-trans isomerase FKBP42
• NCBI Official Symbol: TWD1
• NCBI Official Synonym Symbols: ATFKBP42; FK506-BINDING PROTEIN 42; FKBP42; TWD1; TWISTED DWARF 1; UCU2; ULTRACURVATA 2
• NCBI Protein Information: putative peptidyl-prolyl cis-trans isomerase FKBP42
• UniProt Protein Name: Peptidyl-prolyl cis-trans isomerase FKBP42
• Protein Family: Peptidyl-prolyl cis-trans isomerase
• UniProt Gene Name: FKBP42
• UniProt Synonym Gene Names: TWD1; UCU2; PPIase FKBP42; AtFKBP42
• UniProt Entry Name: FKB42_ARATH

NCBI Description

encodes a 42 kDa FK506-binding protein (AtFKBP42) that possesses similarity to multidomain peptidyl-prolyl cis/trans isomerases (PPIases, EC 5.2.1.8), which are known to be components of mammalian steroid hormone receptor complexes. The protein appears to be localized to the plasma membrane by electron microscopy and binds to HSP90.1 and calmodulin in vitro. It also aggregates citrate synthase in vitro but does NOT show PPIase activity in vivo. Mutants are reduced in size and exhibit disoriented growth in all organs.

Uniprot Description

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (). Modulates the uptake of MRP substrates into the vacuole; reduces metolachlor-GS (MOC-GS) and enhances 17-beta-estradiol 17-(beta-D-glucuronide) (E217betaG) uptake. Regulates cell elongation and orientation. Functions as a positive regulator of PGP1-mediated auxin transport. Confers drug modulation of PGP1 efflux activity as interaction with NPA or flavonol quercetin prevents its physical and functional interaction with PGP1. Required for the proper localization of auxin-related ABCB transporters. Plays a role in brassinosteroid (BR) signaling pathway.