Testing Data
Rabbit IZUMO1 Polyclonal Antibody | anti-IZUMO1 antibody
IZUMO1 Antibody
Gene Names
IZUMO1; OBF; IZUMO
Reactivity
HumanPredicted: Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Synonyms
IZUMO1; Polyclonal Antibody; IZUMO1 Antibody; anti-IZUMO1 antibody
Host
Rabbit
Reactivity
Human
Predicted: Mouse, Rat
Predicted: Mouse, Rat
Clonality
Polyclonal
Form/Format
Purified by protein affinity column containing 1% BSA and 0.02% NaN3
Sequence Length
1695
Applicable Applications for anti-IZUMO1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:20,000-1:80,000
WB: 1:1,000-1:2,000
IHC: 1:100-1:500
WB: 1:1,000-1:2,000
IHC: 1:100-1:500
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
Testing Data
Testing Data
Related Product Information for anti-IZUMO1 antibody
Rabbit polyclonal IZUMO1 (1) antibody was raised against a recombinate human IZUMO1 protein 51-211aa (BC034769).
Product Categories/Family for anti-IZUMO1 antibody
References
(1) Ikram, M.K., Sim, X., Jensen, R.A. et al. Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. PLoS Genet. 6 (10), E1001184 (2010).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
7,339 Da
NCBI Official Full Name
Homo sapiens izumo sperm-egg fusion 1, mRNA
NCBI Official Synonym Full Names
izumo sperm-egg fusion 1
NCBI Official Symbol
IZUMO1
NCBI Official Synonym Symbols
OBF; IZUMO
NCBI Protein Information
izumo sperm-egg fusion protein 1
UniProt Protein Name
Izumo sperm-egg fusion protein 1
Protein Family
UniProt Gene Name
IZUMO1
UniProt Synonym Gene Names
OBF
NCBI Description
The sperm-specific protein Izumo, named for a Japanese shrine dedicated to marriage, is essential for sperm-egg plasma membrane binding and fusion (Inoue et al., 2005 [PubMed 15759005]).[supplied by OMIM, Mar 2008]
Uniprot Description
Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'.
Research Articles on IZUMO1
Similar Products
Product Notes
The IZUMO1 izumo1 (Catalog #AAA859291) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The IZUMO1 Antibody reacts with Human Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's IZUMO1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:20,000-1:80,000 WB: 1:1,000-1:2,000 IHC: 1:100-1:500. Researchers should empirically determine the suitability of the IZUMO1 izumo1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IZUMO1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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