Testing Data
Rabbit TPCN2 Polyclonal Antibody | anti-TPCN2 antibody
TPCN2 Antibody
Gene Names
TPCN2; TPC2; SHEP10
Reactivity
HumanPredicted: Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Synonyms
TPCN2; Polyclonal Antibody; TPCN2 Antibody; anti-TPCN2 antibody
Host
Rabbit
Reactivity
Human
Predicted: Mouse, Rat
Predicted: Mouse, Rat
Clonality
Polyclonal
Form/Format
Purified by peptide affinity column containing 0.5% BSA and 0.02% NaN3
Sequence Length
752
Applicable Applications for anti-TPCN2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
ELISA: 1:20,000-1:80,000
WB: 1:500-1:1,000
IHC: 1:100-1:500
WB: 1:500-1:1,000
IHC: 1:100-1:500
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
Testing Data
Testing Data
Testing Data
Testing Data
Related Product Information for anti-TPCN2 antibody
Rabbit polyclonal TPCN2 (1) antibody was raised was raised against a peptide from N terminal residues of human TPCN2 protein.
Product Categories/Family for anti-TPCN2 antibody
References
(1) Pitt, S.J., Funnell, T.M., Sitsapesan, M., et al. TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+. J. Biol. Chem. 285 (45), 35039-35046 (2010).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
85,243 Da
NCBI Official Full Name
two pore calcium channel protein 2
NCBI Official Synonym Full Names
two pore segment channel 2
NCBI Official Symbol
TPCN2
NCBI Official Synonym Symbols
TPC2; SHEP10
NCBI Protein Information
two pore calcium channel protein 2
UniProt Protein Name
Two pore calcium channel protein 2
Protein Family
UniProt Gene Name
TPCN2
UniProt Synonym Gene Names
TPC2
NCBI Description
This gene encodes a putative cation-selective ion channel with two repeats of a six-transmembrane-domain. The protein localizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calcium ion release from lysosome-related stores. This ubiquitously expressed gene has elevated expression in liver and kidney. Two common nonsynonymous SNPs in this gene strongly associate with blond versus brown hair pigmentation.[provided by RefSeq, Dec 2009]
Uniprot Description
Nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the major voltage-gated Ca2+ channels (VDCC) across the lysosomal membrane. May be involved in smooth muscle contraction.
Research Articles on TPCN2
Similar Products
Product Notes
The TPCN2 tpcn2 (Catalog #AAA859108) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TPCN2 Antibody reacts with Human Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TPCN2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). ELISA: 1:20,000-1:80,000 WB: 1:500-1:1,000 IHC: 1:100-1:500. Researchers should empirically determine the suitability of the TPCN2 tpcn2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TPCN2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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