Western Blot (WB)
(Western blot analysis of extracts from A549 cells, using MAD2L1 antibody.)
anti-Human MAD2L1 Antibody | anti-MAD2L1 antibody
MAD2L1 Antibody
Gene Names
MAD2L1; MAD2; HSMAD2
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
MAD2L1; MAD2L1 Antibody; Mitotic spindle assembly checkpoint protein MAD2A; HsMAD2; Mitotic arrest deficient 2-like protein 1; MAD2-like protein 1; MAD2; anti-MAD2L1 antibody
Reactivity
Human
Specificity
MAD2L1 antibody detects endogenous levels of total MAD2L1 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
205
Applicable Applications for anti-MAD2L1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
ELISA: 1:5000
ELISA: 1:5000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human MAD2L1.
Preparation and Storage
Store at-20 degree C for 1 year.
Western Blot (WB)
(Western blot analysis of extracts from A549 cells, using MAD2L1 antibody.)
Western Blot (WB)
(Western blot analysis of extracts from A549 cells, using MAD2L1 antibody.)
Product Categories/Family for anti-MAD2L1 antibody
References
Li Y., Science 274:246-248(1996). Gemma A., Lung Cancer 32:289-295(2001). Jin D.-Y., Submitted (JUL-1995) to the EMBL/GenBank/DDBJ databases.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
10,335 Da
NCBI Official Full Name
mitotic spindle assembly checkpoint protein MAD2A
NCBI Official Synonym Full Names
mitotic arrest deficient 2 like 1
NCBI Official Symbol
MAD2L1
NCBI Official Synonym Symbols
MAD2; HSMAD2
NCBI Protein Information
mitotic spindle assembly checkpoint protein MAD2A
UniProt Protein Name
Mitotic spindle assembly checkpoint protein MAD2A
Protein Family
UniProt Gene Name
MAD2L1
UniProt Synonym Gene Names
MAD2; HsMAD2; MAD2-like protein 1
NCBI Description
MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. [provided by RefSeq, Jul 2008]
Uniprot Description
Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle attachment and inhibits the activity of the anaphase promoting complex by sequestering CDC20 until all chromosomes are aligned at the metaphase plate.
Research Articles on MAD2L1
Similar Products
Product Notes
The MAD2L1 mad2l1 (Catalog #AAA858037) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The MAD2L1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MAD2L1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500~1:1000 ELISA: 1:5000. Researchers should empirically determine the suitability of the MAD2L1 mad2l1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MAD2L1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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