SDS-Page
(Figure 1. Human CTLA-4 Protein, mFc-His Tag on SDS-PAGE under reducing condition.)
CTLA-4 protein
Human CTLA-4 Protein, mFc-His Tag
Purity
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Synonyms
CTLA-4; Human CTLA-4 Protein; mFc-His Tag; CTLA4; CD152; CTLA-4 protein
Host
HEK293 cells
Purity/Purification
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Form/Format
Lyophilized from sterile PBS, pH 7.4. Normally 5 %-24 % trehalose is added as protectants before lyophilization.
Sequence Positions
CTLA-4 (Gln36-Ser161)+mFc (Pro99-Lys330)
Species
Human
Vector and Tag
C-Mouse Fc and 6xHis tag
Preparation and Storage
Store at -80 degree C for 12 months (Avoid repeated freezing and thawing)
SDS-Page
(Figure 1. Human CTLA-4 Protein, mFc-His Tag on SDS-PAGE under reducing condition.)
SDS-Page
(Figure 1. Human CTLA-4 Protein, mFc-His Tag on SDS-PAGE under reducing condition.)
ELISA (EIA)
(Figure 2. ELISA plate pre-coated by 2ug/ml (100ul/well) Human B7-1, hFc tagged protein (PME100473) can bind Human CTLA4, mFc-His tagged protein (PME100017) in a linear range of 0.048-2.094ng/ml.)
ELISA (EIA)
(Figure 2. ELISA plate pre-coated by 2ug/ml (100ul/well) Human B7-1, hFc tagged protein (PME100473) can bind Human CTLA4, mFc-His tagged protein (PME100017) in a linear range of 0.048-2.094ng/ml.)
ELISA (EIA)
(Figure 3. ELISA plate pre-coated by 2ug/ml (100ul/well) Human B7-2, hFc tagged protein can bind Human CTLA4, mFc-His tagged protein (PME100017) in a linear range of 0.048-2.694ng/ml.)
ELISA (EIA)
(Figure 3. ELISA plate pre-coated by 2ug/ml (100ul/well) Human B7-2, hFc tagged protein can bind Human CTLA4, mFc-His tagged protein (PME100017) in a linear range of 0.048-2.694ng/ml.)
Related Product Information for CTLA-4 protein
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
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Product Notes
The CTLA-4 (Catalog #AAA8575075) is a Protein produced from HEK293 cells and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is CTLA-4 (Gln36-Ser161)+mFc (Pro99-Lys330). It is sometimes possible for the material contained within the vial of "CTLA-4, Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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