Testing Data
(Immunofluorescence staining of methanol-fixed HeLa cells using Synaptotagmin II (Phospho-Thr202) Antibody(E011210, Red).)
Synaptotagmin II Antibody | anti-SYT2 antibody
Synaptotagmin II (Phospho-Thr202) Antibody
Gene Names
SYT2; CMS7; MYSPC; SytII
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Synonyms
Synaptotagmin II; Synaptotagmin II (Phospho-Thr202) Antibody; anti-SYT2 antibody
Reactivity
Human, Mouse, Rat
Specificity
Synaptotagmin II (Phospho-Thr202) Antibody detects endogenous levels of SynaptotagminII only when phosphorylated at threonine202.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
419
Applicable Applications for anti-SYT2 antibody
Immunofluorescence (IF)
Application Notes
IF: 1:100-1:200
Immunogen
The antiserum was produced against synthesized phosphopeptide derived from human Synaptotagmin II around the phosphorylation site of threonine 202 (R-K-TP-L-N).
Preparation and Storage
Store at-20 degree C for 1 year
Testing Data
(Immunofluorescence staining of methanol-fixed HeLa cells using Synaptotagmin II (Phospho-Thr202) Antibody(E011210, Red).)
Testing Data
(Immunofluorescence staining of methanol-fixed HeLa cells using Synaptotagmin II (Phospho-Thr202) Antibody(E011210, Red).)
Product Categories/Family for anti-SYT2 antibody
References
Gustavsson N, et al. Proc Natl Acad Sci U S A. 2008 Mar 11; 105(10):3992-7. Cnops L, et al. Cereb Cortex. 2008 May; 18(5):1221-31. Lynch KL, et al. Mol Biol Cell. 2007 Dec; 18(12):4957-68.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
46,872 Da
NCBI Official Full Name
synaptotagmin-2
NCBI Official Synonym Full Names
synaptotagmin 2
NCBI Official Symbol
SYT2
NCBI Official Synonym Symbols
CMS7; MYSPC; SytII
NCBI Protein Information
synaptotagmin-2
UniProt Protein Name
Synaptotagmin-2
Protein Family
UniProt Gene Name
SYT2
UniProt Synonym Gene Names
SytII
NCBI Description
This gene encodes a synaptic vesicle membrane protein. The encoded protein is thought to function as a calcium sensor in vesicular trafficking and exocytosis. Mutations in this gene are associated with myasthenic syndrome, presynaptic, congenital, with or without motor neuropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Uniprot Description
Exhibits calcium-dependent phospholipid and inositol polyphosphate binding properties (). May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse (). Plays a role in dendrite formation by melanocytes (PubMed:23999003).
Research Articles on SYT2
Similar Products
Product Notes
The SYT2 syt2 (Catalog #AAA857004) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Synaptotagmin II (Phospho-Thr202) Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Synaptotagmin II can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF). IF: 1:100-1:200. Researchers should empirically determine the suitability of the SYT2 syt2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Synaptotagmin II, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
