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Rabbit TJP3 Polyclonal Antibody | anti-TJP3 antibody

TJP3

Gene Names
TJP3; ZO3; ZO-3
Reactivity
Human
Predicted: Rat, Mouse
Applications
ELISA, Western Blot
Purity
Purified By Antigen Affinity Column
Synonyms
TJP3; Polyclonal Antibody; Purified Rabbit Anti Human TJP3 Polyclonal antibody; ZO3; ZO-3; anti-TJP3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Rat, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified By Antigen Affinity Column
Form/Format
Already dissolved in sterile H2O with 1% BSA and 0.02% NaN3 and 50% Glycerol.
Sequence Length
2817
Applicable Applications for anti-TJP3 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA: 1:20000-80000
WB: 1:200-1,000
Immunogen
Recombinant fragment corresponding to 476-637aa of human TJP3.
Cellular Localization
Cell Junction, Cell Membrane, Membrane, Nucleus, Tight Junction
Related Product Information for anti-TJP3 antibody
Homo sapiens tight junction protein 3 (zona occludens 3), mRNA
References
Bonaldo M F, Lennon G, Soares M B. Normalization and subtraction:two approaches to facilitate gene discovery. Genome research. 6 (9):791-806 (1996)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
97kDa
NCBI Official Full Name
Homo sapiens tight junction protein 3 (zona occludens 3), mRNA
NCBI Official Synonym Full Names
tight junction protein 3
NCBI Official Symbol
TJP3
NCBI Official Synonym Symbols
ZO3; ZO-3
NCBI Protein Information
tight junction protein ZO-3
Protein Family

NCBI Description

The protein encoded by this gene is a member of the membrane-associated guanylate kinase-like (MAGUK) protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single guanylate kinase-like (GUK)-domain. In addition, members of the zonula occludens protein subfamily have an acidic domain, a basic arginine-rich region, and a proline-rich domain. The protein encoded by this gene plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This gene has a partial pseudogene on chromosome 1. [provided by RefSeq, May 2012]

Research Articles on TJP3

Similar Products

Product Notes

The TJP3 (Catalog #AAA8563860) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TJP3 reacts with Human Predicted: Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TJP3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:20000-80000 WB: 1:200-1,000. Researchers should empirically determine the suitability of the TJP3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TJP3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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