anti-Human ANP32C Antibody | anti-ANP32C antibody

ANP32C Antibody

Cat. Num. AAA856000

• Gene Names: ANP32C; PP32R1
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Synonyms: ANP32C; ANP32C Antibody; Acidic leucine-rich nuclear phosphoprotein 32 family member C; Phosphoprotein 32-related protein 1; Tumorigenic protein pp32r1; PP32R1; anti-ANP32C antibody

• Reactivity: Human
• Specificity: AN32C antibody detects endogenous levels of total AN32C protein.
• Purity/Purification: Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• Form/Format: In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Sequence Length: 234

• Applicable Applications for anti-ANP32C antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:500-1:1000; ELISA: 1:10000
• Immunogen: The antiserum was produced against synthesized peptide derived from internal of human AN32C.
• Preparation and Storage: Store at-20 degree C for 1 year.

Western Blot (WB)

(Western blot analysis of extracts from HUVEC cells, using AN32C antibody.)

Product Categories/Family for anti-ANP32C antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells

References

Kadkol S.S., Nat. Med. 5:275-279(1999). Kochevar G.J., Hum. Mutat. 23:546-551(2004). Matilla A., Cerebellum 4:7-18(2005).

NCBI and Uniprot Product Information

• NCBI GI #: 6912604
• NCBI GeneID: 23520
• NCBI Accession #: NP_036535.1
• NCBI GenBank Nucleotide #: NM_012403.1
• UniProt Accession #: O43423; Q4W5F9
• Molecular Weight: 26,762 Da
• NCBI Official Full Name: acidic leucine-rich nuclear phosphoprotein 32 family member C
• NCBI Official Synonym Full Names: acidic nuclear phosphoprotein 32 family member C
• NCBI Official Symbol: ANP32C
• NCBI Official Synonym Symbols: PP32R1
• NCBI Protein Information: acidic leucine-rich nuclear phosphoprotein 32 family member C
• UniProt Protein Name: Acidic leucine-rich nuclear phosphoprotein 32 family member C
• Protein Family: Acidic leucine-rich nuclear phosphoprotein 32 family
• UniProt Gene Name: ANP32C
• UniProt Synonym Gene Names: PP32R1

NCBI Description

Phosphoprotein 32 (PP32) is a tumor suppressor that can inhibit several types of cancers, including prostate and breast cancers. The protein encoded by this gene is one of at least two proteins that are similar in amino acid sequence to PP32 and are part of the same acidic nuclear phosphoprotein gene family. However, unlike PP32, the encoded protein is tumorigenic. The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is divergent between PP32 and the protein encoded by this gene. This gene does not contain introns. [provided by RefSeq, Jul 2008]

Uniprot Description

CautionThe His-140 polymorphism is uncertain. It has been found in prostatic cell line without corresponding normal tissue sample. Cells transfected with this variant expressed at least twice as much proteins than native cells.