Rabbit anti-Human SPPL2B Polyclonal Antibody | anti-SPPL2B antibody
SPPL2B (Center) Rabbit pAb
Gene Names
SPPL2B; IMP4; PSH4; PSL1; IMP-4
Reactivity
Human
Applications
Western Blot
Purity
Affinity Purified
Synonyms
SPPL2B; Polyclonal Antibody; SPPL2B (Center) Rabbit pAb; Signal peptide peptidase-like 2B; SPP-like 2B; SPPL2b; 3423-; Intramembrane protease 4; IMP-4; Presenilin homologous protein 4; PSH4; Presenilin-like protein 1; IMP4; KIAA1532; PSL1; anti-SPPL2B antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Ig
Purity/Purification
Affinity Purified
Form/Format
In PBS supplemented with 0.09% (W/V) Sodium Azide.
Sequence Length
511
Applicable Applications for anti-SPPL2B antibody
Western Blot (WB)
Application Notes
WB: 1:2000
Immunogen
This SPPL2B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 196-229 amino acids from the central region of human SPPL2B.
Cellular Localization
Cell Membrane, Endosome, Golgi Apparatus, Lysosome, Membrane
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
signal peptide peptidase-like 2B isoform 3
NCBI Official Synonym Full Names
signal peptide peptidase like 2B
NCBI Official Symbol
SPPL2B
NCBI Official Synonym Symbols
IMP4; PSH4; PSL1; IMP-4
NCBI Protein Information
signal peptide peptidase-like 2B
UniProt Protein Name
Signal peptide peptidase-like 2B
Protein Family
UniProt Gene Name
SPPL2B
UniProt Synonym Gene Names
IMP4; KIAA1532; PSL1
UniProt Entry Name
PSL1_HUMAN
NCBI Description
This gene encodes a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Research Articles on SPPL2B
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Product Notes
The SPPL2B sppl2b (Catalog #AAA8557493) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SPPL2B (Center) Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SPPL2B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:2000. Researchers should empirically determine the suitability of the SPPL2B sppl2b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SPPL2B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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