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Rabbit anti-Human GPAM Polyclonal Antibody | anti-GPAM antibody

GPAM (Center) Rabbit pAb

Gene Names
GPAM; GPAT; GPAT1
Reactivity
Human
Applications
Western Blot, Flow Cytometry, Functional Assay
Purity
Affinity Purified
Synonyms
GPAM; Polyclonal Antibody; GPAM (Center) Rabbit pAb; Glycerol-3-phosphate acyltransferase 1; mitochondrial; GPAT-1; GPAT1; KIAA1560; anti-GPAM antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Ig
Clone Number
RB22518
Purity/Purification
Affinity Purified
Form/Format
Supplied in PBS with 0.09% (W/V) Sodium Azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Length
828
Applicable Applications for anti-GPAM antibody
Western Blot (WB), Flow Cytometry (FC/FACS)
Application Notes
WB: 1:1000
FC/FACS: 1:10-50
Immunogen
This GPAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 426-455 amino acids from the central region of human GPAM.
Cellular Localization
Membrane, Mitochondrion, Mitochondrion Outer Membrane

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
glycerol-3-phosphate acyltransferase 1, mitochondrial
NCBI Official Synonym Full Names
glycerol-3-phosphate acyltransferase, mitochondrial
NCBI Official Symbol
GPAM
NCBI Official Synonym Symbols
GPAT; GPAT1
NCBI Protein Information
glycerol-3-phosphate acyltransferase 1, mitochondrial
UniProt Protein Name
Glycerol-3-phosphate acyltransferase 1, mitochondrial
UniProt Gene Name
GPAM
UniProt Synonym Gene Names
GPAT1; KIAA1560; GPAT-1
UniProt Entry Name
GPAT1_HUMAN

NCBI Description

This gene encodes a mitochondrial enzyme which prefers saturated fatty acids as its substrate for the synthesis of glycerolipids. This metabolic pathway's first step is catalyzed by the encoded enzyme. Two forms for this enzyme exist, one in the mitochondria and one in the endoplasmic reticulum. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]

Uniprot Description

GPAM: glycerol-3-phosphate acyltransferase is an integral multi-pass enzyme of the mitochondrial outer membrane. It performs the first step in de novo phospholipid biosynthesis. Member of the phospholipid and glycerol acyltransferase family

Protein type: Lipid Metabolism - glycerolipid; Mitochondrial; Lipid Metabolism - glycerophospholipid; Membrane protein, multi-pass; Transferase; Membrane protein, integral; EC 2.3.1.15

Chromosomal Location of Human Ortholog: 10q25.2

Cellular Component: mitochondrial outer membrane; mitochondrial inner membrane; integral to membrane; plasma membrane

Molecular Function: glycerol-3-phosphate O-acyltransferase activity

Biological Process: regulation of cytokine secretion; acyl-CoA metabolic process; glycerophospholipid biosynthetic process; triacylglycerol biosynthetic process; cellular lipid metabolic process; positive regulation of multicellular organism growth; fatty acid metabolic process; positive regulation of activated T cell proliferation; fatty acid homeostasis; phospholipid metabolic process; response to glucose stimulus; phosphatidic acid biosynthetic process; CDP-diacylglycerol biosynthetic process; defense response to virus; phospholipid homeostasis

Research Articles on GPAM

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Product Notes

The GPAM gpam (Catalog #AAA8551198) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GPAM (Center) Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GPAM can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Flow Cytometry (FC/FACS). WB: 1:1000 FC/FACS: 1:10-50. Researchers should empirically determine the suitability of the GPAM gpam for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GPAM, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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