Testing Data
Rabbit PHF19 Polyclonal Antibody | anti-PHF19 antibody
PHF19 Antibody
Gene Names
PHF19; PCL3; MTF2L1; TDRD19B
Reactivity
HumanPredicted: Mouse, Rat
Applications
ELISA, Western Blot
Synonyms
PHF19; Polyclonal Antibody; PHF19 Antibody; anti-PHF19 antibody
Host
Rabbit
Reactivity
Human
Predicted: Mouse, Rat
Predicted: Mouse, Rat
Clonality
Polyclonal
Form/Format
Purified by protein affinity column containing 1% BSA and 0.02% NaN3
Sequence Length
2109
Applicable Applications for anti-PHF19 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA: 1:20,000-1:80,000
WB: 1:1,000-1:2,000
WB: 1:1,000-1:2,000
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
Testing Data
Testing Data
Related Product Information for anti-PHF19 antibody
Rabbit polyclonal PHF19 (1) antibody was raised against a recombinate human PHF19 protein 224-519aa (BC125076).
Product Categories/Family for anti-PHF19 antibody
References
(1) Boulay, G., Rosnoblet, C., Guerardel, C. Functional characterization of human Polycomb-like 3 isoforms identifies them as components of distinct EZH2 protein complexes. Biochem. J. 434 (2), 333-342 (2011).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
14,386 Da
NCBI Official Full Name
Homo sapiens PHD finger protein 19, mRNA
NCBI Official Synonym Full Names
PHD finger protein 19
NCBI Official Symbol
PHF19
NCBI Official Synonym Symbols
PCL3; MTF2L1; TDRD19B
NCBI Protein Information
PHD finger protein 19
UniProt Protein Name
PHD finger protein 19
Protein Family
UniProt Gene Name
PHF19
UniProt Synonym Gene Names
PCL3; hPCL3
Uniprot Description
Polycomb group (PcG) that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex. Probably involved in the transition from an active state to a repressed state in embryonic stem cells: acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting H3K36me3 histone demethylases RIOX1 or KDM2B, leading to demethylation of H3K36 and recruitment of the PRC2 complex that mediates H3K27me3 methylation, followed by de novo silencing. Recruits the PRC2 complex to CpG islands and contributes to embryonic stem cell self-renewal. Also binds dimethylated at 'Lys-36' (H3K36me2). Isoform 1 and isoform 2 inhibit transcription from an HSV-tk promoter.
Research Articles on PHF19
Similar Products
Product Notes
The PHF19 phf19 (Catalog #AAA854450) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PHF19 Antibody reacts with Human Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PHF19 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:20,000-1:80,000 WB: 1:1,000-1:2,000. Researchers should empirically determine the suitability of the PHF19 phf19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PHF19, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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