Mouse anti-Human FMR1 Monoclonal Antibody | anti-FMR1 antibody
FMR1 Mouse mAb
Gene Names
FMR1; POF; FMRP; POF1; FRAXA
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Flow Cytometry, Functional Assay, ELISA
Purity
Ascitic Fluid
Synonyms
FMR1; Monoclonal Antibody; FMR1 Mouse mAb; POF; FMRP; POF1; FRAXA; anti-FMR1 antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4G9
Purity/Purification
Ascitic Fluid
Form/Format
Ascitic fluid containing 0.03% Sodium Azide.
Sequence Length
632
Applicable Applications for anti-FMR1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
IHC: 1:200-1:1000
ICC: 1:200-1:1000
ELISA: 1:10000
IHC: 1:200-1:1000
ICC: 1:200-1:1000
ELISA: 1:10000
Immunogen
Purified recombinant fragment of human FMR1 expressed in E. Coli.
Cellular Localization
Cell Junction, Cell Membrane, Cell Projection, Centromere, Chromosome, Cytoplasm, Membrane, Nucleus, Postsynaptic Cell Membrane, Synapse, Synaptosome
Preparation and Storage
Store at 4 degree C short term. Store at -20 degree C long term. Avoid freeze/thaw cycle.
Related Product Information for anti-FMR1 antibody
FMR1, also known as POF, FMRP, FRAXA. Entrez Protein: NP_002015. It is an RNA-binding protein that associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
71kDa
NCBI Official Full Name
Synaptic functional regulator FMR1
NCBI Official Synonym Full Names
FMRP translational regulator 1
NCBI Official Symbol
FMR1
NCBI Official Synonym Symbols
POF; FMRP; POF1; FRAXA
NCBI Protein Information
synaptic functional regulator FMR1
UniProt Protein Name
Fragile X mental retardation protein 1
Protein Family
UniProt Gene Name
FMR1
UniProt Synonym Gene Names
FMRP; Protein FMR-1
UniProt Entry Name
FMR1_HUMAN
NCBI Description
The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]
Research Articles on FMR1
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Product Notes
The FMR1 fmr1 (Catalog #AAA8538512) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The FMR1 Mouse mAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FMR1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA). WB: 1:500-1:2000 IHC: 1:200-1:1000 ICC: 1:200-1:1000 ELISA: 1:10000. Researchers should empirically determine the suitability of the FMR1 fmr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FMR1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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