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Western Blot (WB) (Western blot analysis of extracts from HUVEC cells, using CCKAR antibody.)

CCKAR Antibody | anti-CCKAR antibody

CCKAR Antibody

Gene Names
CCKAR; CCK-A; CCK1R; CCKRA; CCK1-R
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
CCKAR; CCKAR Antibody; CCK-A receptor; CCK-AR; CCKR; CCKRA; cholecystokinin type A receptor; anti-CCKAR antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat
Specificity
CCKAR antibody detects endogenous levels of total CCKAR protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
428
Applicable Applications for anti-CCKAR antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:1000
ELISA: 1:10000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human CCKAR.
Preparation and Storage
Store at-20 degree C for 1 year.

Western Blot (WB)

(Western blot analysis of extracts from HUVEC cells, using CCKAR antibody.)

Western Blot (WB) (Western blot analysis of extracts from HUVEC cells, using CCKAR antibody.)
References
Ulrich C.D., Biochem. Biophys. Res. Commun. 193:204-211(1993). Wank S.A., Biochem. Biophys. Res. Commun. 194:811-818(1993). Miller L.J., Gastroenterology 109:1375-1380(1995).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
886
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
47,841 Da
NCBI Official Full Name
cholecystokinin receptor type A
NCBI Official Synonym Full Names
cholecystokinin A receptor
NCBI Official Symbol
CCKAR
NCBI Official Synonym Symbols
CCK-A; CCK1R; CCKRA; CCK1-R
NCBI Protein Information
cholecystokinin receptor type A
UniProt Protein Name
Cholecystokinin receptor type A
Protein Family
UniProt Gene Name
CCKAR
UniProt Synonym Gene Names
CCKRA; CCK-A receptor; CCK-AR; CCK1-R

NCBI Description

This gene encodes a G-protein coupled receptor that binds non-sulfated members of the cholecystokinin (CCK) family of peptide hormones. This receptor is a major physiologic mediator of pancreatic enzyme secretion and smooth muscle contraction of the gallbladder and stomach. In the central and peripheral nervous system this receptor regulates satiety and the release of beta-endorphin and dopamine. [provided by RefSeq, Jul 2008]

Uniprot Description

Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

Research Articles on CCKAR

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Product Notes

The CCKAR cckar (Catalog #AAA852056) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The CCKAR Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CCKAR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:1000 ELISA: 1:10000. Researchers should empirically determine the suitability of the CCKAR cckar for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCKAR, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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