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Western Blot (WB) (Western blot analysis of extracts from 3T3 cells, using TCF7L1 antibody.)

anti-Human, Mouse TCF7L1 Antibody | anti-TCF7L1 antibody

TCF7L1 Antibody

Gene Names
TCF7L1; TCF3; TCF-3
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Immunogen affinity purified
Synonyms
TCF7L1; TCF7L1 Antibody; Transcription factor 7-like 1; HMG box transcription factor 3; TCF-3; TCF3; anti-TCF7L1 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse
Specificity
TCF7L1 Antibody detects endogenous levels of total TCF7L1
Purity/Purification
Immunogen affinity purified
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
588
Applicable Applications for anti-TCF7L1 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
A synthesized peptide
Preparation and Storage
Store at-20 degree C for 1 year

Western Blot (WB)

(Western blot analysis of extracts from 3T3 cells, using TCF7L1 antibody.)

Western Blot (WB) (Western blot analysis of extracts from 3T3 cells, using TCF7L1 antibody.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
63 KD
NCBI Official Full Name
transcription factor 7-like 1
NCBI Official Synonym Full Names
transcription factor 7 like 1
NCBI Official Symbol
TCF7L1
NCBI Official Synonym Symbols
TCF3; TCF-3
NCBI Protein Information
transcription factor 7-like 1
UniProt Protein Name
Transcription factor 7-like 1
Protein Family
UniProt Gene Name
TCF7L1
UniProt Synonym Gene Names
TCF3; TCF-3

NCBI Description

This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway. The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence. [provided by RefSeq, Nov 2010]

Uniprot Description

Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis (). Down-regulates NQO1, leading to increased mitomycin c resistance.

Research Articles on TCF7L1

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Product Notes

The TCF7L1 tcf7l1 (Catalog #AAA8515277) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The TCF7L1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TCF7L1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the TCF7L1 tcf7l1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TCF7L1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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