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Immunohistochemistry (IHC) (Peptide-+ Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue using CMC1 antibody.)

anti-Human, Mouse CMC1 Antibody | anti-CMC1 antibody

CMC1 Antibody

Gene Names
SLC25A12; AGC1; ARALAR; EIEE39
Reactivity
Human, Mouse
Applications
Immunohistochemistry, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
CMC1; CMC1 Antibody; Calcium-binding mitochondrial carrier protein Aralar1; Mitochondrial aspartate glutamate carrier 1; Solute carrier family 25 member 12; anti-CMC1 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse
Specificity
CMC1 antibody detects endogenous levels of total CMC1 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
678
Applicable Applications for anti-CMC1 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:50-1:100
ELISA: 1:5000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human CMC1.
Preparation and Storage
Store at-20 degree C for 1 year.

Immunohistochemistry (IHC)

(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue using CMC1 antibody.)

Immunohistochemistry (IHC) (Peptide-+ Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue using CMC1 antibody.)
References
Del Arco A., J. Biol. Chem. 273:23327-23334(1998). Kobayashi K., Nat. Genet. 22:159-163(1999). Palmieri L., EMBO J. 20:5060-5069(2001).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
62,720 Da
NCBI Official Full Name
calcium-binding mitochondrial carrier protein Aralar1
NCBI Official Synonym Full Names
solute carrier family 25 member 12
NCBI Official Symbol
SLC25A12
NCBI Official Synonym Symbols
AGC1; ARALAR; EIEE39
NCBI Protein Information
calcium-binding mitochondrial carrier protein Aralar1
UniProt Protein Name
Calcium-binding mitochondrial carrier protein Aralar1
UniProt Gene Name
SLC25A12
UniProt Synonym Gene Names
ARALAR1

NCBI Description

This gene encodes a calcium-binding mitochondrial carrier protein. The encoded protein localizes to the mitochondria and is involved in the exchange of aspartate for glutamate across the inner mitochondrial membrane. Polymorphisms in this gene may be associated with autism, and mutations in this gene may also be a cause of global cerebral hypomyelination. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Apr 2012]

Uniprot Description

Catalyzes the calcium-dependent exchange of cytoplasmic glutamate with mitochondrial aspartate across the mitochondrial inner membrane. May have a function in the urea cycle.

Research Articles on CMC1

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Product Notes

The CMC1 slc25a12 (Catalog #AAA851484) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The CMC1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CMC1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:50-1:100 ELISA: 1:5000. Researchers should empirically determine the suitability of the CMC1 slc25a12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CMC1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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