PDE4A Antibody | anti-PDE4A antibody

PDE4A Antibody

Cat. Num. AAA8504643

• Gene Names: PDE4A; PDE4; DPDE2; PDE46
• Synonyms: PDE4A; PDE4A Antibody; anti-PDE4A antibody

• Sequence Length: 886

NCBI and Uniprot Product Information

• NCBI GI #: 162329608
• NCBI GeneID: 5141
• NCBI Accession #: NP_001104777.1
• NCBI GenBank Nucleotide #: NM_001111307.1
• UniProt Accession #: P27815; O75522; O76092; Q16255; Q16691; Q5DM53; Q6PMT2; Q8IVA7; Q8WUQ3; Q9H3H2
• Molecular Weight: 95,571 Da
• NCBI Official Full Name: cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform 1
• NCBI Official Synonym Full Names: phosphodiesterase 4A
• NCBI Official Symbol: PDE4A
• NCBI Official Synonym Symbols: PDE4; DPDE2; PDE46
• NCBI Protein Information: cAMP-specific 3',5'-cyclic phosphodiesterase 4A
• UniProt Protein Name: cAMP-specific 3',5'-cyclic phosphodiesterase 4A
• Protein Family: cAMP-specific 3',5'-cyclic phosphodiesterase
• UniProt Gene Name: PDE4A
• UniProt Synonym Gene Names: DPDE2

NCBI Description

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]

Uniprot Description

Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.