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Tissue Plasminogen Activator (TPA) Antibody | anti-TPA antibody

Tissue Plasminogen Activator (TPA) Antibody-BIOTIN

Gene Names
PLAT; TPA; T-PA
Purity
>98% pure (SDS-PAGE).
Protein A chromatography
Synonyms
Tissue Plasminogen Activator (TPA); Tissue Plasminogen Activator (TPA) Antibody-BIOTIN; anti-TPA antibody
Ordering
For Research Use Only!
Host
Mouse Ascites
Isotype
IgG
Clone Number
CK8
Specificity
Human tPA.
Purity/Purification
>98% pure (SDS-PAGE).
Protein A chromatography
Form/Format
InIn 0.001M Sodium phosphate, pH 7.4, 0.15M Sodiumchloride.
Sequence Length
19
Immunogen
Recombinant human tPA
Preparation and Storage
Short-term store at 2-8 degree C. Long term store at-20 degree C. Avoid multiple freeze/thaw cycles

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
2,342 Da
NCBI Official Full Name
tPA, partial
NCBI Official Synonym Full Names
plasminogen activator, tissue type
NCBI Official Symbol
PLAT
NCBI Official Synonym Symbols
TPA; T-PA
NCBI Protein Information
tissue-type plasminogen activator
UniProt Protein Name
TPA protein
UniProt Gene Name
tPA

NCBI Description

This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]

Research Articles on TPA

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Product Notes

The TPA tpa (Catalog #AAA850371) is an Antibody produced from Mouse Ascites and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Tissue Plasminogen Activator (TPA), Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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