SYT12 Antibody | anti-SYT12 antibody

SYT12 Antibody

Cat. Num. AAA8503192

• Gene Names: SYT12; SYT11; sytXII
• Synonyms: SYT12; SYT12 Antibody; anti-SYT12 antibody

• Sequence Length: 421

NCBI and Uniprot Product Information

• NCBI GI #: 295444801
• NCBI GeneID: 91683
• NCBI Accession #: NP_001171351.1
• NCBI GenBank Nucleotide #: NM_001177880.1
• UniProt Accession #: Q8IV01
• Molecular Weight: 46,537 Da
• NCBI Official Full Name: synaptotagmin-12 isoform a
• NCBI Official Synonym Full Names: synaptotagmin 12
• NCBI Official Symbol: SYT12
• NCBI Official Synonym Symbols: SYT11; sytXII
• NCBI Protein Information: synaptotagmin-12
• UniProt Protein Name: Synaptotagmin-12
• Protein Family: Synaptotagmin
• UniProt Gene Name: SYT12
• UniProt Synonym Gene Names: SytXII

NCBI Description

This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature.[provided by RefSeq, Apr 2010]

Uniprot Description

May be involved in Ca2+-dependent exocytosis of secretory vesicles through Ca2+ and phospholipid binding to the C2 domain or may serve as Ca2+ sensors in the process of vesicular trafficking and exocytosis.