Typical Testing Data/Standard Curve (for reference only)
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Mammalian Angiotensin II Converting Enzyme (ACE2) Assay Kit | ACE2 assay kit
Angiotensin II Converting Enzyme (ACE2) Activity Assay Kit (Fluorometric)
Reactivity
Mammalian
Synonyms
Angiotensin II Converting Enzyme (ACE2); Angiotensin II Converting Enzyme (ACE2) Activity Assay Kit (Fluorometric); ACE2 Activity Assay kit; ACE2 assay kit
Reactivity
Mammalian
Application Notes
Detection of ACE2 activity in tissue/cell lysates and enzyme preparations
Preparation and Storage
Store at -20 degree C for 12 months.
Typical Testing Data/Standard Curve (for reference only)
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Typical Testing Data/Standard Curve (for reference only)
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Related Product Information for ACE2 assay kit
Background/Introduction: Angiotensin II converting enzyme (ACE2, EC 3.4.17.23), a zinc-based metalloprotease is part of the renin-angiotensin system (RAS) that controls the regulation of blood pressure by cleaving the C-terminal dipeptide of Angiotensin II to convert it into Angiotensin 1-7. ACE2 is a receptor of human coronaviruses, such as SARS and HCoV-NL63. It is expressed on the vascular endothelial cells of lung, kidney and heart. ACE2 is a potential therapeutic target for cardiovascular and coronavirus-induced diseases. ACE2 Activity Assay Kit kit will help the research progress in this field. This kit utilizes the ability of an active ACE2 to cleave a synthetic MCA based peptide substrate to release a free fluorophore. The released MCA can be easily quantified using a fluorescence microplate reader. We also provide an ACE2 specific inhibitor that can differentiate the ACE2 activity from other proteolytic activity.The kit can detect as low as 0.4 mU. Our assay kit is simple and can be used in a high-throughput format.
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Product Notes
The Mammalian ACE2 (Catalog #AAA846865) is an Assay Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA846865 Assay Kit recognizes Mammalian ACE2. Detection of ACE2 activity in tissue/cell lysates and enzyme preparations. Researchers should empirically determine the suitability of the ACE2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Angiotensin II Converting Enzyme (ACE2), Assay Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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