Structure
Apoptosis activator 2 Biochemical
Apoptosis activator 2
Purity
>=98% by HPLC
Synonyms
Apoptosis activator 2; 1-[(3; 4-dichlorophenyl)methyl]indole-2; 3-dione; Apoptosis activator 2 biochemical
Purity/Purification
>=98% by HPLC
Form/Format
Appearance: Orange solid
CAS Number
79183-19-0
Structure Available?
Y
Salt Form
No
Cell-Permeable?
Y
MDL Number
MFCD00141556
PubChem CID
1901244
Solubility/Reconstitution Instructions
DMSO (~ 30 mg/ml)
SMILES
C1=CC=C2C(=C1)C(=O)C(=O)N2CC3=CC(=C(C=C3)Cl)Cl
InChi
InChI=1S/C15H9Cl2NO2/c16-11-6-5-9(7-12(11)17)8-18-13-4-2-1-3-10(13)14(19)15(18)20/h1-7H,8H2
InChi Key
KGRJPLRFGLMQMV-UHFFFAOYSA-N
Handling
Protect from air and light
Preparation and Storage
At -20 degree C
Shelf Life: 36 months
Shelf Life: 36 months
Structure
Structure
Related Product Information for Apoptosis activator 2 biochemical
Background: Apoptosis activator 2 is a cell-permeable apoptosis activator that promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome. Increases procaspase-9 processing and subsequent caspase-3 activation. Induces apoptosis in tumor cells (IC50 = 4 - 9 muM for leukemia cells) with weak or no effect on normal cell lines or those defective/deficient in Apaf-1, caspase-9 or caspase-3 activity (IC?? > 40 muM).
Product Categories/Family for Apoptosis activator 2 biochemical
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Product Notes
The Apoptosis activator 2 (Catalog #AAA842949) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Apoptosis activator 2, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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