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Testing Data

Rabbit Perilipin A Polyclonal Antibody | anti-PLIN1 antibody

Perilipin A Antibody

Gene Names
PLIN1; PERI; PLIN; FPLD4
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Affinity purified
Synonyms
Perilipin A; Polyclonal Antibody; Perilipin A Antibody; Perilipin; Perilipin 1; Perilipin a; Plin1; anti-PLIN1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
100 ug (0.5 mg/ml) affinity purified rabbit anti-Perilipin A polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
Appearance: Colorless liquid
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
522
Applicable Applications for anti-PLIN1 antibody
Western Blot (WB)
Application Notes
Western blot analysis (1-4 ug/ml). However, the optimal conditions should be determined individually. Jurkat cell lysate can be used as a positive control.
Immunogen
Synthetic peptide surrounding amino acid 510 of mouse Perilipin A.
Positive Control
Jurkat cell lysate
Handling
The antibody solution should be gently mixed before use.
Preparation and Storage
At -20 degree C
Shelf Life: 12 months

Testing Data

Testing Data
Related Product Information for anti-PLIN1 antibody
Background: Perilipin is a protein produced and secreted by adipose cells. This protein is localized exclusively to the surface of lipid droplets. In response to lypotic stimuli, perilipin is phosphorylated by protein kinase A. Once activated, perilipin has inhibitory effects on hormone-sensitive lipase (HSL), a protein that mediates the hydrolysis of triacylglycerol, the major form of stored energy in the body. Perilipin expression is limited to adipocytes and steroidogenic cells.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
55,990 Da
NCBI Official Full Name
perilipin
NCBI Official Synonym Full Names
perilipin 1
NCBI Official Symbol
PLIN1
NCBI Official Synonym Symbols
PERI; PLIN; FPLD4
NCBI Protein Information
perilipin-1
UniProt Protein Name
Perilipin-1
Protein Family
UniProt Gene Name
PLIN1
UniProt Synonym Gene Names
PERI; PLIN
UniProt Entry Name
PLIN1_HUMAN

NCBI Description

The protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Feb 2009]

Uniprot Description

perilipin 1: an adipocyte protein of the peripilin family. A modulator of adipocyte lipid metabolism, coating lipid storage droplets to protect them from being broken down by hormone-sensitive lipase. A major cAMP-dependent protein kinase-substrate in adipocytes, also dephosphorylated by PP1. When phosphorylated, may be maximally sensitive to HSL and when unphosphorylated, may play a role in the inhibition of lipolysis.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 15q26

Cellular Component: endoplasmic reticulum; lipid particle; cytosol

Molecular Function: lipid binding

Biological Process: triacylglycerol catabolic process; lipid metabolic process

Disease: Lipodystrophy, Familial Partial, Type 4

Research Articles on PLIN1

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Product Notes

The PLIN1 plin1 (Catalog #AAA840184) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Perilipin An Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Perilipin A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blot analysis (1-4 ug/ml). However, the optimal conditions should be determined individually. Jurkat cell lysate can be used as a positive control. Researchers should empirically determine the suitability of the PLIN1 plin1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Perilipin A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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