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Immunofluorescence (IF) (Immunofluorescent staining of COS7 cells transiently transfected with recombinant RAB17 protein using RAB17 antibody)

Mouse RAB17 Monoclonal Antibody | anti-RAB17 antibody

RAB17 antibody

Applications
Immunohistochemistry, Immunofluorescence
Purity
RAB17 antibody was purified by affinity chromatography.
Synonyms
RAB17; Monoclonal Antibody; RAB17 antibody; Monoclonal RAB17; Anti-RAB17; FLJ12538; OTTHUMP00000202805; Ras related protein RAB17; RAB 17; RAB-17; anti-RAB17 antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3A5
Purity/Purification
RAB17 antibody was purified by affinity chromatography.
Form/Format
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration
500 ug-1 mg/ml (varies by lot)
Sequence Length
212
Applicable Applications for anti-RAB17 antibody
Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
IF: 1:100
IHC: 1:50
Biological Significance
The Rab subfamily of small GTPases plays an important role in the regulation of membrane trafficking. RAB17 is an epithelial cell-specific GTPase.
Cross-Reactivity
Human
Immunogen
RAB17 antibody was raised in mouse using a full length recombinant protein of human RAB17 (NP_071894) produced in HEK293T cells, as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.

Immunofluorescence (IF)

(Immunofluorescent staining of COS7 cells transiently transfected with recombinant RAB17 protein using RAB17 antibody)

Immunofluorescence (IF) (Immunofluorescent staining of COS7 cells transiently transfected with recombinant RAB17 protein using RAB17 antibody)

Western Blot (WB)

(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant RAB17 protein (Right) or empty vector (Left) detected with RAB17 antibody)

Western Blot (WB) (Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant RAB17 protein (Right) or empty vector (Left) detected with RAB17 antibody)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of RAB17 protein in paraffin embedded Human prostate tissue using RAB17 antibody)

Immunohistochemistry (IHC) (Immunohistochemical analysis of RAB17 protein in paraffin embedded Human prostate tissue using RAB17 antibody)
Related Product Information for anti-RAB17 antibody
Mouse monoclonal RAB17 antibody
Product Categories/Family for anti-RAB17 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
9,394 Da
NCBI Official Full Name
ras-related protein Rab-17
NCBI Official Synonym Full Names
RAB17, member RAS oncogene family
NCBI Official Symbol
RAB17
NCBI Protein Information
ras-related protein Rab-17
UniProt Protein Name
Ras-related protein Rab-17
Protein Family
UniProt Gene Name
RAB17
UniProt Entry Name
RAB17_HUMAN

NCBI Description

The Rab subfamily of small GTPases plays an important role in the regulation of membrane trafficking. RAB17 is an epithelial cell-specific GTPase (Lutcke et al., 1993 [PubMed 8486736]).[supplied by OMIM, Oct 2009]

Uniprot Description

RAB17: Might be involved in transcellular transport. Belongs to the small GTPase superfamily. Rab family.

Protein type: G protein, monomeric; G protein; G protein, monomeric, Rab

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: recycling endosome; cell soma; recycling endosome membrane; basolateral plasma membrane; endocytic vesicle; dendrite; early endosome; apical plasma membrane; melanosome; plasma membrane; intracellular

Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding

Biological Process: filopodium formation; metabolic process; regulation of dendrite development; regulation of filopodium formation; transcytosis; endocytic recycling; melanosome transport; intracellular protein transport; regulation of synaptogenesis; regulation of endocytosis; cilium biogenesis; establishment of melanosome localization; Rab protein signal transduction; immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor

Research Articles on RAB17

Similar Products

Product Notes

The RAB17 rab17 (Catalog #AAA834596) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's RAB17 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Immunofluorescence (IF). IF: 1:100 IHC: 1:50. Researchers should empirically determine the suitability of the RAB17 rab17 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RAB17, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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