Western Blot (WB)
(Western blot analysis of Derlin 1 expression in MCF7 (A), mouse liver (B) whole cell lysates.)
Rabbit anti-Human, Mouse Derlin 1 Polyclonal Antibody | anti-DERL1 antibody
Anti-Derlin 1 Antibody
Gene Names
DERL1; DER1; DER-1; derlin-1
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Purified by Immunogen Affinity Chromatography
Synonyms
Derlin 1; Polyclonal Antibody; Anti-Derlin 1 Antibody; DER1; Derlin-1; Degradation in endoplasmic reticulum protein 1; DERtrin-1; Der1-like protein 1; anti-DERL1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of Derlin 1 protein.
Purity/Purification
Purified by Immunogen Affinity Chromatography
Form/Format
Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.
Sequence Length
251
Applicable Applications for anti-DERL1 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant fusion protein of human Derlin 1. The exact sequence is proprietary.
Preparation and Storage
Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of Derlin 1 expression in MCF7 (A), mouse liver (B) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of Derlin 1 expression in MCF7 (A), mouse liver (B) whole cell lysates.)
Related Product Information for anti-DERL1 antibody
Rabbit polyclonal antibody to Derlin 1
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Derlin-1
NCBI Official Synonym Full Names
derlin 1
NCBI Official Symbol
DERL1
NCBI Official Synonym Symbols
DER1; DER-1; derlin-1
NCBI Protein Information
derlin-1
UniProt Protein Name
Derlin-1
Protein Family
UniProt Gene Name
DERL1
UniProt Synonym Gene Names
DER1
UniProt Entry Name
DERL1_HUMAN
NCBI Description
The protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance regulator protein (CFTR) for degradation as well as unfolded proteins in Alzheimer's disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]
Research Articles on DERL1
Similar Products
Product Notes
The DERL1 derl1 (Catalog #AAA8306454) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Derlin 1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Derlin 1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the DERL1 derl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Derlin 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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