VTCN1 recombinant protein
Recombinant Mouse VTCN1 Protein
Gene Names
Vtcn1; B7x; B7h4; B7s1; BC032925
Applications
ELISA, Western Blot, SDS-Page
Purity
>95% as determined by reducing SDS-PAGE
Synonyms
VTCN1; Recombinant Mouse VTCN1 Protein; B7H4; V-set domain-containing T-cell activation inhibitor 1; B7h.5; Immune costimulatory protein B7-H4; Protein B7S1; T-cell costimulatory molecule B7x; VTCN1 recombinant protein
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE
Form/Format
Lyophilized from a 0.2 mum filtered solution of PBS, pH7.4.
Sequence
LIIGFGISGK HFITVTTFTS AGNIGEDGTL SCTFEPDIKL NGIVIQWLKE GIKGLVHEFK EGKDDLSQQH EMFRGRTAVF ADQVVVGNAS LRLKNVQLTD AGTYTCYIRS SKGKGNANLE YKTGAFSMPE INVDYNASSE SLRCEAPRWF PQPTVAWASQ VDQGANFSEV SNTSFELNSE NVTMKVVSVL YNVTINNTYS CMIENDIAKA TGDIKVTDSE VKRRSQLQLL NSVDDIEGRM DEPKSCDKTH TCPPCPAPEL LGGPSVFLFP PKPKDTLMIS RTPEVTCVVV DVSHEDPEVK FNWYVDGVEV HNAKTKPREE QYNSTYRVVS VLTVLHQDWL NGKEYKCKVS NKALPAPIEK TISKAKGQPR EPQVYTLPPS REEMTKNQVS LTCLVKGFYP SDIAVEWESN GQPENNYKTT PPVLDSDGSF FLYSKLTVDK SRWQQGNVFS CSVMHEALHN HYTQKSLSLS PGK
Sequence Length
283
Applicable Applications for VTCN1 recombinant protein
ELISA (EIA), Western Blot (WB), SDS-PAGE
Endotoxin
Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Preparation and Storage
Lyophilized protein should be stored at -20 degree C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 2-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at -20 degree C for 3 months.
Reconstituted protein solution can be stored at 2-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at -20 degree C for 3 months.
Related Product Information for VTCN1 recombinant protein
Recombinant Mouse VTCN1 Protein is produced by mammalian expression system and the target gene encoding Leu25-Ser256 is expressed with a Fc tag at the C-terminus.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
V-set domain containing T-cell activation inhibitor 1
NCBI Official Synonym Full Names
V-set domain containing T cell activation inhibitor 1
NCBI Official Symbol
Vtcn1
NCBI Official Synonym Symbols
B7x; B7h4; B7s1; BC032925
NCBI Protein Information
V-set domain containing T-cell activation inhibitor 1
UniProt Protein Name
V-set domain containing T-cell activation inhibitor 1
Protein Family
UniProt Gene Name
Vtcn1
UniProt Synonym Gene Names
B7-H4
Uniprot Description
VTCN1: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor- associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation. Belongs to the immunoglobulin superfamily. BTN/MOG family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 3|3 F2.2
Cellular Component: external side of plasma membrane
Molecular Function: receptor binding
Biological Process: negative regulation of T cell activation; positive regulation of T cell proliferation; response to protozoan
Research Articles on VTCN1
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Product Notes
The VTCN1 vtcn1 (Catalog #AAA8305358) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's VTCN1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), SDS-PAGE. Researchers should empirically determine the suitability of the VTCN1 vtcn1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: LIIGFGISGK HFITVTTFTS AGNIGEDGTL SCTFEPDIKL NGIVIQWLKE GIKGLVHEFK EGKDDLSQQH EMFRGRTAVF ADQVVVGNAS LRLKNVQLTD AGTYTCYIRS SKGKGNANLE YKTGAFSMPE INVDYNASSE SLRCEAPRWF PQPTVAWASQ VDQGANFSEV SNTSFELNSE NVTMKVVSVL YNVTINNTYS CMIENDIAKA TGDIKVTDSE VKRRSQLQLL NSVDDIEGRM DEPKSCDKTH TCPPCPAPEL LGGPSVFLFP PKPKDTLMIS RTPEVTCVVV DVSHEDPEVK FNWYVDGVEV HNAKTKPREE QYNSTYRVVS VLTVLHQDWL NGKEYKCKVS NKALPAPIEK TISKAKGQPR EPQVYTLPPS REEMTKNQVS LTCLVKGFYP SDIAVEWESN GQPENNYKTT PPVLDSDGSF FLYSKLTVDK SRWQQGNVFS CSVMHEALHN HYTQKSLSLS PGK. It is sometimes possible for the material contained within the vial of "VTCN1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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