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IgG4 Fc Recombinant Protein | IgG4 recombinant protein

Recombinant Human IgG4 Fc Protein

Applications
ELISA, Western Blot, SDS-Page
Purity
>95% as determined by reducing SDS-PAGE
Synonyms
IgG4 Fc; Recombinant Human IgG4 Fc Protein; Ig gamma-4 chain C region; IgG4 recombinant protein
Ordering
For Research Use Only!
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE
Form/Format
Lyophilized from a 0.2 mum filtered solution of 20mM PB, 150mM NaCl, pH7.4.
Sequence
PPCPSCPAPE FLGGPSVFLF PPKPKDTLMI SRTPEVTCVV VDVSQEDPEV QFNWYVDGVE VHNAKTKPRE EQFNSTYRVV SVLTVLHQDW LNGKEYKCKV SNKGLPSSIE KTISKAKGQP REPQVYTLPP SQEEMTKNQV SLTCLVKGFY PSDIAVEWES NGQPENNYKT TPPVLDSDGS FFLYSRLTVD KSRWQEGNVF SCSVMHEALH NHYTQKSLSL SPGK
Sequence Length
327
Applicable Applications for IgG4 recombinant protein
ELISA (EIA), Western Blot (WB), SDS-PAGE
Endotoxin
Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Directions for use
Always centrifuge tubes befoe opening. Do not mix vortex or pipetting. It is not recommended to reconstitute to a concentration less then 100 ug/mL. Dissolve the lyophilized protein in ddH2O. PLease aliqiuot the reconstituted solution to minimize freeze-thaw cycles.
Preparation and Storage
Lyophilized protein should be stored at -20 degree C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 2-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at -20 degree C for 3 months.
Related Product Information for IgG4 recombinant protein
Recombinant Human IgG4 Fc Protein is produced by mammalian expression system and the target gene encoding Pro104-Lys327 (Leu325Pro) is expressed

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Immunoglobulin heavy constant gamma 4
NCBI Official Synonym Full Names
immunoglobulin heavy constant gamma 4 (G4m marker)
NCBI Official Symbol
IGHG4
UniProt Protein Name
Ig gamma-4 chain C region
UniProt Gene Name
IGHG4
UniProt Entry Name
IGHG4_HUMAN

Uniprot Description

IGHG4:

Chromosomal Location of Human Ortholog: 14q32.33

Cellular Component: extracellular space; extracellular region

Molecular Function: antigen binding

Biological Process: innate immune response; complement activation, classical pathway; complement activation

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Product Notes

The IgG4 ighg4 (Catalog #AAA8305017) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's IgG4 Fc can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), SDS-PAGE. Researchers should empirically determine the suitability of the IgG4 ighg4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: PPCPSCPAPE FLGGPSVFLF PPKPKDTLMI SRTPEVTCVV VDVSQEDPEV QFNWYVDGVE VHNAKTKPRE EQFNSTYRVV SVLTVLHQDW LNGKEYKCKV SNKGLPSSIE KTISKAKGQP REPQVYTLPP SQEEMTKNQV SLTCLVKGFY PSDIAVEWES NGQPENNYKT TPPVLDSDGS FFLYSRLTVD KSRWQEGNVF SCSVMHEALH NHYTQKSLSL SPGK. It is sometimes possible for the material contained within the vial of "IgG4 Fc, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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