SGTA recombinant protein

Recombinant Human SGTA Protein

Cat. Num. AAA8249786

• Gene Names: SGTA; SGT; hSGT; alphaSGT
• Reactivity: Human
• Applications: ELISA, Western Blot, SDS-Page
• Purity: Greater than 95% as determined by reducing SDS-PAGE.
• Synonyms: SGTA; Recombinant Human SGTA Protein; SGT; SGT1; Small glutamine-rich tetratricopeptide repeat-containing protein alpha; Alpha-SGT; Vpu-binding protein; UBP; SGTA recombinant protein

• Host: E Coli
• Reactivity: Human
• Purity/Purification: Greater than 95% as determined by reducing SDS-PAGE.
• Form/Format: Lyophilized from a 0.2 muM filtered solution of 20mM Tris, 150mM NaCl, pH 8.0.
• Sequence: MGSSHHHHHH SSGLVPRGSH MDNKKRLAYA IIQFLHDQLR HGGLSSDAQE SLEVAIQCLE TAFGVTVEDS DLALPQTLPE IFEAAATGKE MPQDLRSPAR TPPSEEDSAE AERLKTEGNE QMKVENFEAA VHFYGKAIEL NPANAVYFCN RAAAYSKLGN YAGAVQDCER AICIDPAYSK AYGRMGLALS SLNKHVEAVA YYKKALELDP DNETYKSNLK IAELKLREAP SPTGGVGSFD IAGLLNNPGF MSMASNLMNN PQIQQLMSGM ISGGNNPLGT PGTSPSQNDL ASLIQAGQQF AQQMQQQNPE LIEQLRSQIR SRTPSASNDD QQE
• Sequence Length: 313

• Applicable Applications for SGTA recombinant protein: ELISA (EIA),Western Blot (WB), SDS-PAGE, Mass Spectrometry (MS)
• Endotoxin: Less than 0.1 ng/mug (1 IEU/mug) as determined by LAL test.
• Directions for Use: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 mug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Preparation and Storage: Lyophilized protein should be stored at -20 degree C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 2-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at -20 degree C for 3 months.

Related Product Information for SGTA recombinant protein

Recombinant Human SGTA Protein is produced by our E Coli expression system and the target gene encoding Met1-Glu313 is expressed with a 6His tag at the N-terminus.

NCBI and Uniprot Product Information

• NCBI GI #: 4506921
• NCBI GeneID: 6449
• NCBI Accession #: NP_003012.1
• NCBI GenBank Nucleotide #: NM_003021.3
• UniProt Accession #: O43765; Q6FIA9; Q9BTZ9; D6W610
• Molecular Weight: 34,063 Da
• NCBI Official Full Name: small glutamine-rich tetratricopeptide repeat-containing protein alpha
• NCBI Official Synonym Full Names: small glutamine rich tetratricopeptide repeat containing alpha
• NCBI Official Symbol: SGTA
• NCBI Official Synonym Symbols: SGT; hSGT; alphaSGT
• NCBI Protein Information: small glutamine-rich tetratricopeptide repeat-containing protein alpha
• UniProt Protein Name: Small glutamine-rich tetratricopeptide repeat-containing protein alpha
• Protein Family: Small glutamine-rich tetratricopeptide repeat-containing protein
• UniProt Gene Name: SGTA
• UniProt Synonym Gene Names: SGT; SGT1; UBP
• UniProt Entry Name: SGTA_HUMAN

NCBI Description

This gene encodes a protein which is capable of interacting with the major nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate protein; however, its function is not known. Since this transcript is expressed ubiquitously in various tissues, this protein may serve a housekeeping function. [provided by RefSeq, Jul 2008]

Uniprot Description

SGTA: Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. Homooligomerize. Interacts with NS1 from parvovirus H-1, with Vpu and Gag from HIV-1. Interacts with SARS- CoV accessory protein 7a. Interacts with DNAJC5 and DNAJC5B. Ubiquitous. Belongs to the SGT family.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 19p13

Cellular Component: cytoplasm; cytosol; membrane; nucleus

Molecular Function: protein binding