CNDP1 recombinant protein

Recombinant Human CNDP1 Protein

Cat. Num. AAA8248808

• Gene Names: CNDP1; CN1; CPGL2; HsT2308
• Reactivity: Human
• Applications: ELISA, Western Blot, SDS-Page
• Purity: Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
• Synonyms: CNDP1; Recombinant Human CNDP1 Protein; CN1; CPGL2; Beta-Ala-His dipeptidase; CNDP dipeptidase 1; Carnosine dipeptidase 1; Glutamate carboxypeptidase-like protein 2; Serum carnosinase; CNDP1 recombinant protein

• Host: Human cells
• Reactivity: Human
• Purity/Purification: Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
• Form/Format: Supplied as a 0.2 muM filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 7.5.
• Sequence: SPSPPPALLE KVFQYIDLHQ DEFVQTLKEW VAIESDSVQP VPRFRQELFR MMAVAADTLQ RLGARVASVD MGPQQLPDGQ SLPIPPVILA ELGSDPTKGT VCFYGHLDVQ PADRGDGWLT DPYVLTEVDG KLYGRGATDN KGPVLAWINA VSAFRALEQD LPVNIKFIIE GMEEAGSVAL EELVEKEKDR FFSGVDYIVI SDNLWISQRK PAITYGTRGN SYFMVEVKCR DQDFHSGTFG GILHEPMADL VALLGSLVDS SGHILVPGIY DEVVPLTEEE INTYKAIHLD LEEYRNSSRV EKFLFDTKEE ILMHLWRYPS LSIHGIEGAF DEPGTKTVIP GRVIGKFSIR LVPHMNVSAV EKQVTRHLED VFSKRNSSNK MVVSMTLGLH PWIANIDDTQ YLAAKRAIRT VFGTEPDMIR DGSTIPIAKM FQEIVHKSVV LIPLGAVDDG EHSQNEKINR WNYIEGTKLF AAFFLEMAQL HVDHHHHHH
• Sequence Length: 507

• Applicable Applications for CNDP1 recombinant protein: ELISA (EIA),Western Blot (WB), SDS-PAGE, Mass Spectrometry (MS)
• Endotoxin: Less than 0.1 ng/mug (1 IEU/mug) as determined by LAL test.
• Directions for Use: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 mug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Preparation and Storage: Lyophilized protein should be stored at -20 degree C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 2-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at -20 degree C for 3 months.

Related Product Information for CNDP1 recombinant protein

Recombinant Human CNDP1 Protein is produced by our Mammalian expression system and the target gene encoding Pro28-His507 is expressed with a 6His tag at the C-terminus.

NCBI and Uniprot Product Information

• NCBI GI #: 21071039
• NCBI GeneID: 84735
• NCBI Accession #: NP_116038.4
• NCBI GenBank Nucleotide #: NM_032649.5
• UniProt Accession #: Q96KN2; Q14D40; Q17S05; Q2TBG0; Q6UWK2; Q9BT98
• Molecular Weight: 56,706 Da
• NCBI Official Full Name: beta-Ala-His dipeptidase
• NCBI Official Synonym Full Names: carnosine dipeptidase 1
• NCBI Official Symbol: CNDP1
• NCBI Official Synonym Symbols: CN1; CPGL2; HsT2308
• NCBI Protein Information: beta-Ala-His dipeptidase
• UniProt Protein Name: Beta-Ala-His dipeptidase
• Protein Family: Beta-Ala-His dipeptidase
• UniProt Gene Name: CNDP1
• UniProt Synonym Gene Names: CN1; CPGL2
• UniProt Entry Name: CNDP1_HUMAN

NCBI Description

This gene encodes a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This gene contains trinucleotide (CTG) repeat length polymorphism in the coding region. [provided by RefSeq, Jul 2008]

Uniprot Description

CNDP1: a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This gene contains trinucleotide (CTG) repeat length polymorphism in the coding region. [provided by RefSeq, Jul 2008]

Protein type: Amino Acid Metabolism - histidine; EC 3.4.13.20; Other Amino Acids Metabolism - beta-alanine; Protease; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 18q22.3

Cellular Component: cytosol

Molecular Function: dipeptidase activity; zinc ion binding

Biological Process: peptide catabolic process; proteolysis; regulation of cellular protein metabolic process