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Western Blot (WB) (Western blot analysis of CD185 expression in NIH3T3 (A) whole cell lysates.)

Rabbit anti-Human, Mouse CD185 Polyclonal Antibody | anti-CXCR5 antibody

Anti-CD185 Antibody

Gene Names
CXCR5; BLR1; CD185; MDR15
Reactivity
Human, Mouse
Applications
Western Blot
Purity
The antibody was purified by affinity chromatography.
Synonyms
CD185; Polyclonal Antibody; Anti-CD185 Antibody; BLR1; MDR15; C-X-C chemokine receptor type 5; CXC-R5; CXCR-5; Burkitt lymphoma receptor 1; Monocyte-derived receptor 15; MDR-15; anti-CXCR5 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of CD185 protein.
Purity/Purification
The antibody was purified by affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Sequence Length
372
Applicable Applications for anti-CXCR5 antibody
Western Blot (WB)
Application Notes
WB: 1/500 - 1/2000
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD185. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of CD185 expression in NIH3T3 (A) whole cell lysates.)

Western Blot (WB) (Western blot analysis of CD185 expression in NIH3T3 (A) whole cell lysates.)
Related Product Information for anti-CXCR5 antibody
Rabbit polyclonal antibody to CD185

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
643
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
36,676 Da
NCBI Official Full Name
C-X-C chemokine receptor type 5 isoform 1
NCBI Official Synonym Full Names
C-X-C motif chemokine receptor 5
NCBI Official Symbol
CXCR5
NCBI Official Synonym Symbols
BLR1; CD185; MDR15
NCBI Protein Information
C-X-C chemokine receptor type 5
UniProt Protein Name
C-X-C chemokine receptor type 5
Protein Family
UniProt Gene Name
CXCR5
UniProt Synonym Gene Names
BLR1; MDR15; CXC-R5; CXCR-5; MDR-15
UniProt Entry Name
CXCR5_HUMAN

NCBI Description

This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

Uniprot Description

CXCR5: Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 11q23.3

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; protein binding

Biological Process: cell motility; positive regulation of cytokinesis

Research Articles on CXCR5

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Product Notes

The CXCR5 cxcr5 (Catalog #AAA8248227) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CD185 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD185 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1/500 - 1/2000. Researchers should empirically determine the suitability of the CXCR5 cxcr5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD185, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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