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Western Blot (WB) (Western blot analysis of CAP18 expression in mouse liver (A) whole cell lysates.)

Rabbit anti-Human, Mouse CAP18 Polyclonal Antibody | anti-CAMP antibody

Anti-CAP18 Antibody

Gene Names
CAMP; LL37; CAP18; CRAMP; HSD26; CAP-18; FALL39; FALL-39
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry
Purity
The antibody was purified by immunogen affinity chromatography.
Synonyms
CAP18; Polyclonal Antibody; Anti-CAP18 Antibody; FALL39; Cathelicidin antimicrobial peptide; 18 kDa cationic antimicrobial protein; CAP-18; hCAP-18; anti-CAMP antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of CAP18 protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Sequence Length
170
Applicable Applications for anti-CAMP antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1/500 - 1/2000; IHC: 1/50 - 1/200
Immunogen
Recombinant full length protein of human CAP18
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of CAP18 expression in mouse liver (A) whole cell lysates.)

Western Blot (WB) (Western blot analysis of CAP18 expression in mouse liver (A) whole cell lysates.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of CAP18 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of CAP18 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
Related Product Information for anti-CAMP antibody
Rabbit polyclonal antibody to CAP18

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
820
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
19,301 Da
NCBI Official Full Name
cathelicidin antimicrobial peptide preproprotein
NCBI Official Synonym Full Names
cathelicidin antimicrobial peptide
NCBI Official Symbol
CAMP
NCBI Official Synonym Symbols
LL37; CAP18; CRAMP; HSD26; CAP-18; FALL39; FALL-39
NCBI Protein Information
cathelicidin antimicrobial peptide
UniProt Protein Name
Cathelicidin antimicrobial peptide
UniProt Gene Name
CAMP
UniProt Synonym Gene Names
hCAP-18
UniProt Entry Name
CAMP_HUMAN

NCBI Description

This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation. [provided by RefSeq, Sep 2014]

Uniprot Description

CAMP: Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. Belongs to the cathelicidin family.

Protein type: Vesicle; Secreted, signal peptide; Secreted; Cell cycle regulation

Chromosomal Location of Human Ortholog: 3p21.3

Cellular Component: cell wall; extracellular region; extracellular space; intracellular; specific granule

Molecular Function: protein binding

Biological Process: antibacterial humoral response; antifungal humoral response; cell redox homeostasis; chronic inflammatory response; defense response to bacterium; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; innate immune response; innate immune response in mucosa; killing by host of symbiont cells; response to yeast

Research Articles on CAMP

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Product Notes

The CAMP camp (Catalog #AAA8245600) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-CAP18 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CAP18 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1/500 - 1/2000; IHC: 1/50 - 1/200. Researchers should empirically determine the suitability of the CAMP camp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CAP18, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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