Calpain 11 Blocking Peptide | CAPN11 blocking peptide
Calpain 11 Blocking Peptide
NCBI and Uniprot Product Information
NCBI Description
Calpains constitute a family of intracellular calcium-dependent cysteine proteases. There are eight members in this superfamily. They consist of a variable 80 kDa subunit and an invariant 30 kDa subunit. This calpain protein appears to have protease activity and calcium-binding ability. A similar mouse protein may play a functional role in spermatogenesis and in the regulation of calcium-dependent signal transduction events during meiosis. [provided by RefSeq, Dec 2008]
Uniprot Description
CAPN11: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Belongs to the peptidase C2 family.
Protein type: EC 3.4.22.-; Protease
Chromosomal Location of Human Ortholog: 6p12
Cellular Component: acrosome
Molecular Function: calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; peptidase activity
Biological Process: proteolysis
Research Articles on CAPN11
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Product Notes
The CAPN11 capn11 (Catalog #AAA8243989) is a Blocking Peptide produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. The Calpain 11 Blocking Peptide reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Calpain 11 can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours. Researchers should empirically determine the suitability of the CAPN11 capn11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Calpain 11, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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