NFYC blocking peptide

NFYC Blocking Peptide

Cat. Num. AAA824218

• Gene Names: NFYC; HSM; CBFC; HAP5; CBF-C; NF-YC; H1TF2A
• Reactivity: Human, Mouse, Rat, Zebrafish
• Applications: Blocking (BL)
• Purity: >85%
• Synonyms: NFYC; NFYC Blocking Peptide; Nuclear transcription factor Y subunit gamma; CAAT box DNA-binding protein subunit C; Nuclear transcription factor Y subunit C; NF-YC; Transactivator HSM-1/2; NFYC blocking peptide

• Host: Synthetic
• Reactivity: Human, Mouse, Rat, Zebrafish
• Purity/Purification: >85%
• Form/Format: Lyophilized powder
• Sequence Length: 334

• Applicable Applications for NFYC blocking peptide: Blocking (BL)
• Application Notes: Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
• Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
• Preparation and Storage: Shipped at 4 degree C. Store at -20 degree C for one year.

Related Product Information for NFYC blocking peptide

The peptide is used to block Anti-NFYC Antibody reactivity.

NCBI and Uniprot Product Information

• NCBI GI #: 217272829
• NCBI GeneID: 4802
• NCBI Accession #: NP_001136059.1
• NCBI GenBank Nucleotide #: NM_001142587.1
• UniProt Accession #: Q13952; Q59GY4; Q5T6K8; Q5T6K9; Q5T6L1; Q5TZR6; Q92869; Q9HBX1; B4DUS6; B4DW63; D3DPV9; F8VWM3
• Molecular Weight: 37,066 Da
• NCBI Official Full Name: nuclear transcription factor Y subunit gamma isoform 3
• NCBI Official Synonym Full Names: nuclear transcription factor Y, gamma
• NCBI Official Symbol: NFYC
• NCBI Official Synonym Symbols: HSM; CBFC; HAP5; CBF-C; NF-YC; H1TF2A
• NCBI Protein Information: nuclear transcription factor Y subunit gamma; transactivator HSM-1; transactivator HSM-1/2; CCAAT binding factor subunit C; transcription factor NF-Y, C subunit; CAAT box DNA-binding protein subunit C; nuclear transcription factor Y subunit C; CCAAT transcription binding factor subunit gamma; histone H1 transcription factor large subunit 2A
• UniProt Protein Name: Nuclear transcription factor Y subunit gamma
• Protein Family: Nuclear transcription factor
• UniProt Gene Name: NFYC
• UniProt Synonym Gene Names: NF-YC
• UniProt Entry Name: NFYC_HUMAN

NCBI Description

This gene encodes one subunit of a trimeric complex forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoters of a variety of genes. The encoded protein, subunit C, forms a tight dimer with the B subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

Uniprot Description

NFYC: Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes. Belongs to the NFYC/HAP5 subunit family. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 1p32

Cellular Component: nucleoplasm; CCAAT-binding factor complex; nucleus

Molecular Function: protein binding; DNA binding; sequence-specific DNA binding; protein heterodimerization activity; transcription coactivator activity; transcription factor activity; transcription factor binding

Biological Process: regulation of transcription from RNA polymerase II promoter; protein folding; regulation of transcription, DNA-dependent; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; cellular lipid metabolic process