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ARHGEF5 blocking peptide

ARHGEF5 Blocking Peptide

Gene Names
ARHGEF5; P60; TIM; GEF5; TIM1
Reactivity
Human, Mouse, Rat
Applications
Blocking (BL)
Purity
>85%
Synonyms
ARHGEF5; ARHGEF5 Blocking Peptide; TIM; Rho guanine nucleotide exchange factor 5; Ephexin-3; Guanine nucleotide regulatory protein TIM; Oncogene TIM; Transforming immortalized mammary oncogene; p60 TIM; ARHGEF5 blocking peptide
Ordering
For Research Use Only!
Host
Synthetic
Reactivity
Human, Mouse, Rat
Purity/Purification
>85%
Form/Format
Lyophilized powder
Sequence Length
1597
Applicable Applications for ARHGEF5 blocking peptide
Blocking (BL)
Application Notes
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Related Product Information for ARHGEF5 blocking peptide
The peptide is used to block Anti-ARHGEF5 Antibody reactivity.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
60,056 Da
NCBI Official Full Name
rho guanine nucleotide exchange factor 5
NCBI Official Synonym Full Names
Rho guanine nucleotide exchange factor (GEF) 5
NCBI Official Symbol
ARHGEF5
NCBI Official Synonym Symbols
P60; TIM; GEF5; TIM1
NCBI Protein Information
rho guanine nucleotide exchange factor 5; p60 TIM; ephexin-3; oncogene TIM; guanine nucleotide regulatory protein TIM; transforming immortalized mammary oncogene
UniProt Protein Name
Rho guanine nucleotide exchange factor 5
UniProt Gene Name
ARHGEF5
UniProt Synonym Gene Names
TIM
UniProt Entry Name
ARHG5_HUMAN

NCBI Description

Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. [provided by RefSeq, Jul 2008]

Uniprot Description

ARHGEF5: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Oncoprotein; GEFs, Rac/Rho; Motility/polarity/chemotaxis; GEFs

Chromosomal Location of Human Ortholog: 7q35

Molecular Function: Rho guanyl-nucleotide exchange factor activity; protein binding; GTP binding

Biological Process: myeloid dendritic cell chemotaxis; actin cytoskeleton organization and biogenesis

Research Articles on ARHGEF5

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Product Notes

The ARHGEF5 arhgef5 (Catalog #AAA824107) is a Blocking Peptide produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. The ARHGEF5 Blocking Peptide reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ARHGEF5 can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours. Researchers should empirically determine the suitability of the ARHGEF5 arhgef5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ARHGEF5, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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